ASXL genes and RUNX1: an intimate connection?

被引：10
|
作者：
Metzeler, Klaus H. [1 ]
机构：
[1] Univ Munich, D-81377 Munich, Germany
来源：
BLOOD | 2014年 / 124卷 / 09期
关键词：
ACUTE MYELOID-LEUKEMIA; OLDER PATIENTS; MUTATIONS;
D O I：
10.1182/blood-2014-07-586073
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Micol et al report the discovery of mutations in the additional sex combs-like 2 (ASXL2) gene in about one-quarter of acute myeloid leukemia (AML) patients carrying the t(8;21) translocation.
引用
收藏
页码：1382 / 1383
页数：2
相关论文
共 50 条
  • [21] SCL and RUNX1 regulate RUNX1 gene expression by association to RUNX1-P1 promoter
    Gutierrez, S.
    Martinez, M.
    FEBS JOURNAL, 2014, 281 : 689 - 689
  • [22] ETV6/RUNX1 dysiregulates genes with RUNX1 binding site via mechanism reversible by histone deacetylase inhibitors.
    Starkova, Julia
    Madzo, Jozef
    Cario, Gunnar
    Zaliova, Marketa
    Ford, Anthony
    Trka, Jan
    BLOOD, 2006, 108 (11) : 631A - 631A
  • [23] RUNX1 as a recombinase cofactor
    Cieslak, Agata
    Payet-Bornet, Dominique
    Asnafi, Vahid
    ONCOTARGET, 2015, 6 (26) : 21793 - 21794
  • [24] Transcription factor RUNX1
    E. N. Markova
    N. V. Petrova
    S. V. Razin
    O. L. Kantidze
    Molecular Biology, 2012, 46 : 755 - 767
  • [25] Runx1 blocks elongation
    不详
    NATURE IMMUNOLOGY, 2006, 7 (01) : 17 - 17
  • [26] RUNX1-RUNX1 homodimerization modulates RUNX1 activity and function
    Li, Donglan
    Sinha, Kislay K.
    Hay, Maher A.
    Rinaldi, Ciro R.
    Saunthararajah, Yogen
    Nucifora, Giuseppina
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (18) : 13542 - 13551
  • [27] Chromatin regulation by RUNX1
    Lichtinger, Monika
    Hoogenkamp, Maarten
    Krysinska, Hanna
    Ingram, Richard
    Bonifer, Constanze
    BLOOD CELLS MOLECULES AND DISEASES, 2010, 44 (04) : 287 - 290
  • [28] RUNX1 and breast cancer
    Mercado-Matos, Jose
    Matthew-Onabanjo, Asia N.
    Shaw, Leslie M.
    ONCOTARGET, 2017, 8 (23): : 36934 - +
  • [29] Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation
    Krutein, Michelle C.
    Hart, Matthew R.
    Anderson, Donovan J.
    Jeffery, Jasmin
    Kotini, Andriana G.
    Dai, Jin
    Chien, Sylvia
    DelPriore, Michaela
    Borst, Sara
    Maguire, Jean Ann
    French, Deborah L.
    Gadue, Paul
    Papapetrou, Eirini P.
    Keel, Sioban B.
    Becker, Pamela S.
    Horwitz, Marshall S.
    BLOOD ADVANCES, 2021, 5 (03) : 687 - 699
  • [30] Transcription factor RUNX1
    Markova, E. N.
    Petrova, N. V.
    Razin, S. V.
    Kantidze, O. L.
    MOLECULAR BIOLOGY, 2012, 46 (06) : 755 - 767
12345