Triple composite tumor of stomach: A rare combination of alpha fetoprotein positive hepatoid adenocarcinoma, tubular adenocarcinoma and large cell neuroendocrine carcinoma

被引:7
|
作者
Lipi, Lipika [1 ]
Sachdev, Ritesh [1 ]
Gautam, Dheeraj [1 ]
Singh, Jasbir [1 ]
Mohapatra, Ishani [1 ]
机构
[1] Medanta, Dept Pathol & Lab Med, Gurgaon, Haryana, India
关键词
Alpha fetoprotein; composite tumors; hepatoid adenocarcinoma; neuroendocrine;
D O I
10.4103/0377-4929.130912
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A 50-year-old male patient presented with pain abdomen of 6 months duration. Computed tomography scan revealed a large mass in the stomach occluding the lumen. Histopathology revealed a triple composite tumor comprising of tubular adenocarcinoma arising on a background of high-grade dysplasia, hepatoid adenocarcinoma (positive for Hep Par-1 and alpha fetoprotein) and large cell neuroendocrine carcinoma (positive for synaptophysin and chromogranin) with nodal metastasis. Triple composite tumors are distinctly rare with few reports in literature.
引用
收藏
页码:98 / 100
页数:3
相关论文
共 50 条
  • [21] Emphasis on the clinical relationship between alpha-fetoprotein and hepatoid adenocarcinoma of the stomach: a retrospective study
    Lamei Li
    Xinle Yang
    Wei Ji
    Qi Zhu
    Xin Yang
    Junqi Niu
    Wanyu Li
    BMC Gastroenterology, 23
  • [22] Emphasis on the clinical relationship between alpha-fetoprotein and hepatoid adenocarcinoma of the stomach: a retrospective study
    Li, Lamei
    Yang, Xinle
    Ji, Wei
    Zhu, Qi
    Yang, Xin
    Niu, Junqi
    Li, Wanyu
    BMC GASTROENTEROLOGY, 2023, 23 (01)
  • [23] A Rare Case of Large Cell Neuroendocrine Carcinoma of the Colon Masquerading as Adenocarcinoma
    Khan, Bilal
    Qureshi, Mariyam
    Amjad, Qasim Manzoor
    Shahbaz, Muhammad Usman
    Rehman, Khalil Ur
    Basit, Muhammad Abdul
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (10): : S1633 - S1633
  • [24] Composite large cell neuroendocrine carcinoma and adenocarcinoma of the common bile duct
    Sato, K
    Waseda, R
    Tatsuzawa, Y
    Fujinaga, H
    Wakabayashi, T
    Ueda, Y
    Katsuda, S
    JOURNAL OF CLINICAL PATHOLOGY, 2006, 59 (01) : 105 - 107
  • [25] Unusual variant of non-small cell lung carcinoma: Alpha-fetoprotein-producing hepatoid adenocarcinoma
    Udovicic-Gagula, D.
    Redzepagic, J.
    Bilalovic, N.
    VIRCHOWS ARCHIV, 2015, 467 : S251 - S252
  • [26] Alpha-Fetoprotein (AFP)-Negative Hepatoid Adenocarcinoma of the Stomach and its Associated Uncommon Features With a Review
    Rajasekaran, Pavithra
    Pattnaik, Bramhadatta
    Mishra, Monica
    Shahin, Mohammed
    Mishra, Pritinanda
    Ayyanar, Pavithra
    INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2023, 31 (05) : 872 - 878
  • [27] Simultaneous Large Cell Neuroendocrine Carcinoma and Adenocarcinoma of the Stomach: A Case Report and Literature Review
    Nakazuru, S.
    Matsumura, Y.
    Harada, Y.
    Iwasaki, R.
    Iwasaki, T.
    Nishio, K.
    Hasegawa, H.
    Sakakibara, Y.
    Yamada, T.
    Nishikawa, K.
    Ishida, H.
    Mori, K.
    Mita, E.
    NEUROENDOCRINOLOGY, 2015, 102 (1-2) : 152 - 152
  • [28] Collision tumour of large-cell neuroendocrine carcinoma and adenocarcinoma in the stomach: A case report
    Payet, Eduardo
    Pilco, Pau I.
    Montes, Jaime
    Cordero-Morales, Alejandra
    Jose Savitzky, Maria
    Stenning-Persivale, Karoline
    ECANCERMEDICALSCIENCE, 2016, 10
  • [29] HEPATOID ADENOCARCINOMA - A DISTINCTIVE HISTOLOGICAL SUBTYPE OF ALPHA-FETOPROTEIN-PRODUCING LUNG-CARCINOMA
    ISHIKURA, H
    KANDA, M
    ITO, M
    NOSAKA, K
    MIZUNO, K
    VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1990, 417 (01) : 73 - 80
  • [30] Large Cell Neuroendocrine Tumor Mixed with Adenocarcinoma of the Transverse Colon: A Rare Occurrence
    Gill, Jefferey
    Small, Michael
    Geerken, Reynaldo
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 : S314 - S314