Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

被引:0
|
作者
Wang, Tianshi [1 ]
Pfeiffer, Tom [2 ]
Daemen, Joost [1 ]
Mastik, Frits [1 ]
Wieser, Wolfgang [3 ]
Van der Steen, A. F. W. [1 ,4 ,5 ]
Huber, Robert [2 ]
Van Soest, Gijs [1 ]
机构
[1] Erasmus MC, Thoraxctr, POB 2040, NL-3000 CA Rotterdam, Netherlands
[2] Univ Lubeck, Inst Biomed Opt, Peter Monnik Weg 4, D-23562 Lubeck, Germany
[3] Optores GmbH, Gollierstr 70, D-80339 Munich, Germany
[4] Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China
[5] Delft Univ Technol, Dept Imaging Sci & Technol, Postbus 5, NL-2600 AA Delft, Netherlands
关键词
SPECKLE DECORRELATION; BLOOD-FLOW; HIGH-SPEED;
D O I
10.1117/12.2506151
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/ s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.
引用
收藏
页数:5
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