A Characterization of Minimum Spanning Tree-Like Metric Spaces

被引:1
|
作者
Hayamizu, Momoko [1 ]
Endo, Hiroshi [2 ]
Fukumizu, Kenji [3 ]
机构
[1] Grad Univ Adv Studies, SOKENDAI, Dept Stat Sci, Tokyo, Japan
[2] Kyoto Univ, Dept Clin Applicat, Ctr iPS Cell Res & Applicat CiRA, Kyoto, Japan
[3] Inst Stat Math, Tokyo, Japan
关键词
Cellular differentiation; distance-based tree estimation; minimum spanning tree; four-point condition; fourth-point condition; CELL FATE DECISIONS; HIERARCHY;
D O I
10.1109/TCBB.2016.2550431
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Recent years have witnessed a surge of biological interest in the minimum spanning tree (MST) problem for its relevance to automatic model construction using the distances between data points. Despite the increasing use of MST algorithms for this purpose, the goodness-of-fit of an MST to the data is often elusive because no quantitative criteria have been developed to measure it. Motivated by this, we provide a necessary and sufficient condition to ensure that a metric space on n points can be represented by a fully labeled tree on n vertices, and thereby determine when an MST preserves all pairwise distances between points in a finite metric space.
引用
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页码:468 / 471
页数:4
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