Current status of antiretroviral therapy

被引:61
|
作者
Temesgen, Zelalem [1 ]
Warnke, David [1 ]
Kasten, Mary J. [1 ]
机构
[1] Mayo Clin & Mayo Fdn, Div Infect Dis, Rochester, MN 55905 USA
关键词
antiretrovirals; antiretroviral therapy; chemokine receptor antagonists; entry inhibitors; fusion inhibitors; highly active antiretroviral therapy; HIV; integrase inhibitors; maturation inhibitors; non-nucleoside analogue reverse transcriptase inhibitors; nucleoside analogue reverse transcriptase inhibitors; protease inhibitors; treatment guidelines;
D O I
10.1517/14656566.7.12.1541
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
At present, there are 22 FDA-approved antiretroviral agents, which are categorised into four classes of drugs. Several others are in various stages of basic and clinical development. The authors of this paper review the general characteristics of each class of antiretrovirals, as well as individual investigational agents that are in advanced clinical development. A brief synopsis of US and WHO antiretroviral treatment guidelines is also provided.
引用
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页码:1541 / 1554
页数:14
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