At present, there are 22 FDA-approved antiretroviral agents, which are categorised into four classes of drugs. Several others are in various stages of basic and clinical development. The authors of this paper review the general characteristics of each class of antiretrovirals, as well as individual investigational agents that are in advanced clinical development. A brief synopsis of US and WHO antiretroviral treatment guidelines is also provided.
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Univ London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, EnglandUniv London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, England
Wilson, S. L.
Scullard, G.
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St Marys NHS Trust, Dept GU Med & Communicable Dis, London, EnglandUniv London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, England
Scullard, G.
Fidler, S. J.
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Univ London Imperial Coll Sci Technol & Med, Div Med, Dept GUM & HIV, London W2 1PG, EnglandUniv London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, England
Fidler, S. J.
Weber, J. N.
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Univ London Imperial Coll Sci Technol & Med, Div Med, Dept GUM & HIV, London W2 1PG, EnglandUniv London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, England
Weber, J. N.
Poulter, N. R.
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Univ London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, EnglandUniv London Imperial Coll Sci Technol & Med, Int Ctr Circulatory Hlth, London W2 1PG, England