Immune evasion of the CD1d/NKT cell axis

被引：14

作者：

Brutkiewicz, Randy R. ^{[1
]}

Yunes-Medina, Laura ^{[1
]}

Liu, Jianyun ^{[1
]}

机构：

[1] Indiana Univ Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2018年 / 52卷

基金：

美国国家卫生研究院;

关键词：

KILLER T-CELLS; CD1D-MEDIATED ANTIGEN PRESENTATION; IMMUNODEFICIENCY-VIRUS-INFECTION; NKT CELLS; DENDRITIC CELLS; MURINE CYTOMEGALOVIRUS; LISTERIA-MONOCYTOGENES; ADAPTIVE IMMUNITY; MULTIPLE-MYELOMA; CYTOPLASMIC TAIL;

D O I：

10.1016/j.coi.2018.04.021

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.

引用

页码：87 / 92

页数：6

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