Immune evasion of the CD1d/NKT cell axis

被引：14

作者：

Brutkiewicz, Randy R. ^{[1
]}

Yunes-Medina, Laura ^{[1
]}

Liu, Jianyun ^{[1
]}

机构：

[1] Indiana Univ Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2018年 / 52卷

基金：

美国国家卫生研究院;

关键词：

KILLER T-CELLS; CD1D-MEDIATED ANTIGEN PRESENTATION; IMMUNODEFICIENCY-VIRUS-INFECTION; NKT CELLS; DENDRITIC CELLS; MURINE CYTOMEGALOVIRUS; LISTERIA-MONOCYTOGENES; ADAPTIVE IMMUNITY; MULTIPLE-MYELOMA; CYTOPLASMIC TAIL;

D O I：

10.1016/j.coi.2018.04.021

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.

引用

页码：87 / 92

页数：6

共 50 条

[1] Blocking the innate immune CD1d/NKT cell axis prevents the development of cortical hyperexcitability and posttraumatic epilepsy
Ping, Xingjie
Xiong, Wenhui
Priya, Raj
Liu, Jianyun
Wyatt-Johnson, Season K.
Brutkiewicz, Randy R.
Jin, Xiaoming
EPILEPSIA, 2025,
[2] The influence of CD1d in postselection NKT cell maturation and homeostasis
McNab, FW
Berzins, SP
Pellicci, DG
Kyparissoudis, K
Field, K
Smyth, MJ
Godfrey, DI
JOURNAL OF IMMUNOLOGY, 2005, 175 (06): : 3762 - 3768
[3] Polymorphisms in the CD1d Promoter That Regulate CD1d Gene Expression Are Associated with Impaired NKT Cell Development
Borg, Zachary D.
Benoit, Patrick J.
Lilley, Graham W. J.
Aktan, Idil
Chant, Alan
DeVault, Victoria L.
Rincon, Mercedes
Boyson, Jonathan E.
JOURNAL OF IMMUNOLOGY, 2014, 192 (01): : 189 - 199
[4] Targeted disruption of CD1d prevents NKT cell development in pigs
Guan Yang
Bianca L. Artiaga
Timothy J. Hackmann
Melissa S. Samuel
Eric M. Walters
Shahram Salek-Ardakani
John P. Driver
Mammalian Genome, 2015, 26 : 264 - 270
[5] Targeted disruption of CD1d prevents NKT cell development in pigs
Yang, Guan
Artiaga, Bianca L.
Hackmann, Timothy J.
Samuel, Melissa S.
Walters, Eric M.
Salek-Ardakani, Shahram
Driver, John P.
MAMMALIAN GENOME, 2015, 26 (5-6) : 264 - 270
[6] CD1d expression and invariant NKT cell responses in herpesvirus infections
Chung, Brian K.
Priatel, John J.
Tan, Rusung
FRONTIERS IN IMMUNOLOGY, 2015, 6
[7] CD1d antigen presentation: treats for NKT cells
Dale I Godfrey
James McCluskey
Jamie Rossjohn
Nature Immunology, 2005, 6 : 754 - 756
[8] Understanding and exploiting the NKT:CD1d system in disease
Exley, M.
IMMUNOLOGY, 2014, 143 : 15 - 15
[9] CD1d antigen presentation: treats for NKT cells
Godfrey, DI
McCluskey, J
Rossjohn, J
NATURE IMMUNOLOGY, 2005, 6 (08) : 754 - 756
[10] Glycolipid antigen-presentation by CD1d and mechanism of NKT cell activation
Zajonc, Dirk
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250

← 1 2 3 4 5 →