Hepatitis C virus infection in intravenous drug users

被引：17
|
作者：
Harder, J
Walter, E
Riecken, B
Ihling, C
Bauer, TM
机构：
[1] Univ Freiburg, Med Klin, Innere Med Abt 2, Dept Pathol, D-79106 Freiburg, Germany
[2] Univ Freiburg, Univ Hosp, Dept Med Gastroenterol Hepatol & Infect Dis 2, Freiburg, Germany
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2004年 / 10卷 / 08期
关键词：
drug users; hepatitis C; liver function tests; liver histology;
D O I：
10.1111/j.1469-0691.2004.00934.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Intravenous drug use (IVDU) remains a major means of hepatitis C virus (HCV) transmission. In this study, 101 drug users were studied prospectively after cessation of IVDU. Of these, 75.8% were anti-HCV positive, and 71.4% had elevated levels of alanine aminotransferase. These levels decreased significantly within 1 month of IVDU cessation (p 0.02). Liver biopsies showed minimal or mild fibrosis in 32 (71%) of 45 subjects, and severe fibrosis in two (4.4%) subjects. Anti-HCV-positive intravenous drug users in this study presented with mild liver disease and variable stages of disease progression. Biochemical disease activity might be affected by IVDU.
引用
收藏
页码：768 / 770
页数：3
相关论文
共 50 条
  • [41] What is the cost utility of screening for hepatitis C virus (HCV) in intravenous drug users?
    Leal, P
    Stein, K
    Rosenberg, W
    JOURNAL OF MEDICAL SCREENING, 1999, 6 (03) : 124 - 131
  • [42] Hepatitis C virus eradication in intravenous drug users maintained with subcutaneous naltrexone implants
    Jeffrey, Gary P.
    MacQuillan, Gerry
    Chua, Fern
    Galhenage, Sam
    Bull, Judith
    Young, Emma
    Hulse, Gary
    O'Neil, George
    HEPATOLOGY, 2007, 45 (01) : 111 - 117
  • [43] Epidemiological changes in hepatitis C virus genotypes in France:: evidence in intravenous drug users
    Bourlière, M
    Barberin, JM
    Rotily, M
    Guagliardo, V
    Portal, I
    Lecomte, L
    Benali, S
    Boustière, C
    Perrier, H
    Jullien, M
    Lambot, G
    Loyer, R
    LeBars, O
    Daniel, R
    Khiri, H
    Halfon, P
    JOURNAL OF VIRAL HEPATITIS, 2002, 9 (01) : 62 - 70
  • [44] High hepatitis C virus prevalence and incidence among Canadian intravenous drug users
    Roy, E.
    Alary, M.
    Morissette, C.
    Leclerc, P.
    Boudreau, J. -F.
    Parent, R.
    Rochefort, J.
    Claessens, C.
    INTERNATIONAL JOURNAL OF STD & AIDS, 2007, 18 (01) : 23 - 27
  • [45] HEPATITIS C VIRUS REINFECTION FOLLOWING SUSTAINED VIROLOGICAL RESPONSE IN INTRAVENOUS DRUG USERS
    Manolakopoulos, S.
    Kranidioti, H.
    Karatapanis, S.
    Tsirogianni, E.
    Goulis, J.
    Deutsch, M.
    Anagnostou, O.
    Margaritopoulos, D.
    Papatheodoridis, G.
    Pectasides, D.
    JOURNAL OF HEPATOLOGY, 2012, 56 : S532 - S532
  • [46] IgM antibody response to the hepatitis C virus core protein in intravenous drug users
    Toniutto, P
    Falleti, E
    Gasparini, V
    Fabris, C
    Tisminetzky, SG
    Lombardelli, T
    Pacco, P
    Satta, A
    Pirisi, M
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1999, 33 (02) : 69 - 73
  • [47] Molecular Characterization of Hepatitis C Virus Core Region in Moroccan Intravenous Drug Users
    Trimbitas, Roxana-Delia
    Fayssel, Naouar
    Serghini, Fatima-Zahra
    Wakrim, Lahcen
    Khyatti, Meriem
    Essalhi, Mohammed
    Meziane Bellefquih, Abdelkrim
    Benani, Abdelouaheb
    JOURNAL OF MEDICAL VIROLOGY, 2016, 88 (08) : 1376 - 1383
  • [48] Hepatitis C among intravenous drug users - Response
    Hagan, H
    Des Jarlais, DC
    Thiede, H
    EPIDEMIOLOGY, 2005, 16 (03) : 424 - 424
  • [49] Treatment of acute C hepatitis in intravenous drug users
    Bargiacchi, O
    Audagnotto, S
    Garazzino, S
    De Rosa, FG
    JOURNAL OF HEPATOLOGY, 2005, 43 (01) : 186 - 187
  • [50] National guidelines for the management of hepatitis C virus infection in drug users in Slovenia
    Maticic, Mojca
    Kastelic, Andrej
    ZDRAVNISKI VESTNIK-SLOVENIAN MEDICAL JOURNAL, 2009, 78 (10): : 529 - 539
12345