A novel synthesis of 2-fluoroalkyl quinolines

被引：0
|
作者：
Wang, QF [1 ]
Mao, YY [1 ]
Qin, CY [1 ]
Zhu, SZ [1 ]
Hu, CM [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
来源：
MONATSHEFTE FUR CHEMIE | 2000年 / 131卷 / 01期
关键词：
alpha-fluoroalkyl aldehyde; alpha-fluoroalkyl cyclohexanone; aniline; 2-fluoroalkyl quinoline; 2-fluoroalkyl benzoxazole; acetic acid;
D O I：
10.1007/s007060050006
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
2-Fluoroalkyl quinolines are prepared by reacting aniline with alpha-fluoroalkyl aldehydes or alpha-fluoroalkyl cyclohexanones in the presence of acetic acid. Under the same reaction condition, 2-aminophenol gives the corresponding 2-fluoroalkyl-8-quinolinols; in some cases, 2-fluoroalkyl benzoxazoles are also formed as minor products.
引用
收藏
页码：55 / 63
页数：9
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