A novel synthesis of 2-fluoroalkyl quinolines

被引：0

作者：

Wang, QF ^{[1
]}

Mao, YY ^{[1
]}

Qin, CY ^{[1
]}

Zhu, SZ ^{[1
]}

Hu, CM ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

来源：

MONATSHEFTE FUR CHEMIE | 2000年 / 131卷 / 01期

关键词：

alpha-fluoroalkyl aldehyde; alpha-fluoroalkyl cyclohexanone; aniline; 2-fluoroalkyl quinoline; 2-fluoroalkyl benzoxazole; acetic acid;

D O I：

10.1007/s007060050006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-Fluoroalkyl quinolines are prepared by reacting aniline with alpha-fluoroalkyl aldehydes or alpha-fluoroalkyl cyclohexanones in the presence of acetic acid. Under the same reaction condition, 2-aminophenol gives the corresponding 2-fluoroalkyl-8-quinolinols; in some cases, 2-fluoroalkyl benzoxazoles are also formed as minor products.

引用

页码：55 / 63

页数：9

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