Kinetic constants and sample-to-sample variation in the rate of metabolism of two or more substrates for human liver microsomal CYP1A2, CYP2B6, CYP2C8, CYP2C9, and CYP3A4

被引：0
|
作者：
Woodworth, Zell [1 ]
Dwyer, L. Anne [1 ]
Collins, Lisa [1 ]
Graves, Terry [1 ]
Helmstetter, Stephanie [1 ]
Ogilvie, Brian [1 ]
Otwell, Clayton [1 ]
Pope, Chad [1 ]
Ramsey, Tiffin [1 ]
Yerino, Phyllis [1 ]
Parkinson, Andrew [1 ]
机构：
[1] XenoTech LLC, Lenexa, KS USA
来源：
DRUG METABOLISM REVIEWS | 2006年 / 38卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
107
引用
收藏
页码：64 / 64
页数：1
相关论文
共 50 条
  • [21] Effects of anthocyanidins and anthocyanins on the expression and catalytic activities of CYP2A6, CYP2B6, CYP2C9, and CYP3A4 in primary human hepatocytes and human liver microsomes
    Anzenbacherova, E. (eva.anzenbacherova@upol.cz), 1600, American Chemical Society (62):
  • [22] Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues
    DeLozier, Tracy C.
    Kissling, Grace E.
    Coulter, Sherry J.
    Dai, Diana
    Foley, Julie F.
    Bradbury, J. Alyce
    Murphy, Elizabeth
    Steenbergen, Charles
    Zeldin, Darryl C.
    Goldstein, Joyce A.
    DRUG METABOLISM AND DISPOSITION, 2007, 35 (04) : 682 - 688
  • [23] Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype
    Kiang, Tony K. L.
    Ho, Ping C.
    Anari, M. Reza
    Tong, Vincent
    Abbott, Frank S.
    Chang, Thomas K. H.
    TOXICOLOGICAL SCIENCES, 2006, 94 (02) : 261 - 271
  • [24] Enzyme kinetics of valproic acid metabolism by human cDNA CYP2A6, CYP2B6, and CYP2C9*1
    Ho, PC
    Chang, TKH
    Abbott, FS
    DRUG METABOLISM REVIEWS, 2002, 34 : 112 - 112
  • [25] The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro
    Muschler, Eugen
    Lal, Jawahar
    Jetter, Alexander
    Rattay, Anke
    Zanger, Ulrich
    Zadoyan, Gregor
    Fuhr, Uwe
    Kirchheiner, Julia
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2009, 105 (06) : 374 - 379
  • [26] Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype
    Kiang, TKL
    Abbott, FS
    Ho, PC
    Chang, TKH
    FASEB JOURNAL, 2005, 19 (05): : A1112 - A1112
  • [27] Effects of Panax notoginseng Saponins on the Activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in Rats In Vivo
    Liu, Rui
    Qin, Mengnan
    Hang, Pengzhou
    Liu, Yan
    Zhang, Zhiren
    Liu, Gaofeng
    PHYTOTHERAPY RESEARCH, 2012, 26 (08) : 1113 - 1118
  • [28] Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes
    Lim, HK
    Duczak, N
    Brougham, L
    Elliot, M
    Patel, K
    Chan, K
    DRUG METABOLISM AND DISPOSITION, 2005, 33 (08) : 1211 - 1219
  • [29] CONTRIBUTION OF UGT1A1, CYP2A6, CYP2C9, AND CYP3A4 IN METABOLISM OF BELINOSTAT
    Luo, Gang
    Schicker, Michael
    Lee, Deborah
    Leitz, Sara
    McKenzie, Donald
    Albaugh, Daniel
    Reddy, Guru
    DRUG METABOLISM AND PHARMACOKINETICS, 2019, 34 (01) : S59 - S59
  • [30] Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes
    Drocourt, L
    Ourlin, JC
    Pascussi, JM
    Maurel, P
    Vilarem, MJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (28) : 25125 - 25132
12345