Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype

被引：0
|
作者：
Kiang, TKL [1 ]
Abbott, FS [1 ]
Ho, PC [1 ]
Chang, TKH [1 ]
机构：
[1] Univ British Columbia, Vancouver, BC V6T 1Z3, Canada
来源：
FASEB JOURNAL | 2005年 / 19卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A1112 / A1112
页数：1
相关论文
共 50 条
  • [1] Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype
    Kiang, Tony K. L.
    Ho, Ping C.
    Anari, M. Reza
    Tong, Vincent
    Abbott, Frank S.
    Chang, Thomas K. H.
    TOXICOLOGICAL SCIENCES, 2006, 94 (02) : 261 - 271
  • [2] Enzyme kinetics of valproic acid metabolism by human cDNA CYP2A6, CYP2B6, and CYP2C9*1
    Ho, PC
    Chang, TKH
    Abbott, FS
    DRUG METABOLISM REVIEWS, 2002, 34 : 112 - 112
  • [3] The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients
    Tan, Lan
    Yu, Jin-Tai
    Sun, Yan-Ping
    Ou, Jiang-Rong
    Song, Jing-Hui
    Yu, Yang
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2010, 112 (04) : 320 - 323
  • [4] CONTRIBUTION OF UGT1A1, CYP2A6, CYP2C9, AND CYP3A4 IN METABOLISM OF BELINOSTAT
    Luo, Gang
    Schicker, Michael
    Lee, Deborah
    Leitz, Sara
    McKenzie, Donald
    Albaugh, Daniel
    Reddy, Guru
    DRUG METABOLISM AND PHARMACOKINETICS, 2019, 34 (01) : S59 - S59
  • [5] Warfarin resistance with poor CYP2C9 activity and CYP2C9*1*2 genotype
    Dericioglu, N
    Babaoglu, MO
    Saygi, S
    Bozkurt, A
    Yasar, U
    ANNALS OF PHARMACOTHERAPY, 2004, 38 (05) : 899 - 899
  • [6] Application of Vivid™ fluorogenic substrates for the in vitro assessment of CYP2C9*1, CYP2C9*2 and CYP2C9*3 metabolism
    Thompson, DV
    Marks, BD
    Goossens, TA
    Trubetskoy, OV
    DRUG METABOLISM REVIEWS, 2002, 34 : 153 - 153
  • [7] Influence of CYP2C9 and CYP2A6 on plasma concentrations of valproic acid: a meta-analysis
    Ha Young Yoon
    Min Hyoung Ahn
    Jeong Yee
    Nari Lee
    Ji Min Han
    Hye Sun Gwak
    European Journal of Clinical Pharmacology, 2020, 76 : 1053 - 1058
  • [8] Influence of CYP2C9 and CYP2A6 on plasma concentrations of valproic acid: a meta-analysis
    Yoon, Ha Young
    Ahn, Min Hyoung
    Yee, Jeong
    Lee, Nari
    Han, Ji Min
    Gwak, Hye Sun
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 76 (08) : 1053 - 1058
  • [9] Safety of voriconazole in a patient with CYP2C9*2/CYP2C9*2 genotype
    Geist, Marcus J. P.
    Egerer, Gerlinde
    Burhenne, Juergen
    Mikus, Gerd
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (09) : 3227 - 3228
  • [10] Role of CYP2C9 and its variants (CYP2C9*3 and CYP2C9*13) in the metabolism of lornoxicam in humans
    Guo, YJ
    Zhang, YF
    Wang, Y
    Chen, XY
    Si, DY
    Zhong, DF
    Fawcett, JP
    Zhou, H
    DRUG METABOLISM AND DISPOSITION, 2005, 33 (06) : 749 - 753
12345