Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype

被引:0
|
作者
Kiang, TKL [1 ]
Abbott, FS [1 ]
Ho, PC [1 ]
Chang, TKH [1 ]
机构
[1] Univ British Columbia, Vancouver, BC V6T 1Z3, Canada
来源
FASEB JOURNAL | 2005年 / 19卷 / 05期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A1112 / A1112
页数:1
相关论文
共 50 条
  • [21] Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes
    Hijazi, Y
    Boulieu, R
    DRUG METABOLISM AND DISPOSITION, 2002, 30 (07) : 853 - 858
  • [22] Genetic variability of CYP2D6, CYP2B6, CYP2C9 and CYP2C19 genes across the Italian Peninsula
    Carano, Francesco
    Sarno, Stefania
    De Fanti, Sara
    Serventi, Patrizia
    Bini, Carla
    Luiselli, Donata
    Pelotti, Susi
    ANNALS OF HUMAN BIOLOGY, 2018, 45 (01) : 66 - 71
  • [23] Effects of Anthocyanidins and Anthocyanins on the Expression and Catalytic Activities of CYP2A6, CYP2B6, CYP2C9, and CYP3A4 in Primary Human Hepatocytes and Human Liver Microsomes
    Srovnalova, Alzbeta
    Svecarova, Michaela
    Zapletalova, Michaela Kopecna
    Anzenbacher, Pavel
    Bachleda, Petr
    Anzenbacherova, Eva
    Dvorak, Zdenek
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 62 (03) : 789 - 797
  • [25] Metabolism of dapsone by CYP2C9 and its effect on CYP2C9 substrates.
    Tracy, TS
    Metz, CA
    Korzekwa, KR
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1998, 63 (02) : 152 - 152
  • [26] High-throughput screening assays for the assessment of CYP2C9*1, CYP2C9*2, and CYP2C9*3 metabolism using fluorogenic Vivid® substrates
    Marks, BD
    Thompson, DV
    Goossens, TA
    Trubetskoy, OV
    JOURNAL OF BIOMOLECULAR SCREENING, 2004, 9 (05) : 439 - 449
  • [27] Catalytic roles of CYP2C9 and its variants (CYP2C9*2 and CYP2C9*3) in lornoxicam 5′-hydroxylation
    Iida, I
    Miyata, A
    Arai, M
    Hirota, M
    Akimoto, M
    Higuchi, S
    Kobayashi, K
    Chiba, K
    DRUG METABOLISM AND DISPOSITION, 2004, 32 (01) : 7 - 9
  • [28] The Effect of UGT 1A9, CYP2B6 and CYP2C9 Genes Polymorphism on Propofol Pharmacokinetics in Children
    Pavlovic, Dimitrije
    Budic, Ivana
    Stoimenov, Tatjana Jevtovic
    Stokanovic, Dragana
    Marjanovic, Vesna
    Stevic, Marija
    Slavkovic, Milan
    Simic, Dusica
    PHARMACOGENOMICS & PERSONALIZED MEDICINE, 2020, 13 : 13 - 27
  • [29] Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment
    Crettol, S
    Déglon, JJ
    Besson, J
    Croquette-Krokkar, M
    Gothuey, I
    Hämmig, R
    Monnat, M
    Hüttemann, H
    Baumann, P
    Eap, CB
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 78 (06) : 593 - 604
  • [30] The role of CYP2C9 genotype and of drugs possibly interacting on CYP2C9 for severe hypoglycaemia
    Reimann, IR
    Tschetwertak, N
    Hippius, M
    Fünfstück, R
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2005, 371 : R138 - R138