Rituximab in post allogeneic hematopoietic stem cell transplantation membranous nephropathy: a case report

被引：1
|
作者：
Vischini, Gisella [1 ]
Cudillo, Laura [2 ]
Ferrannini, Michele [1 ]
Di Daniele, Nicola [1 ]
Cerretti, Raffaella [2 ]
Arcese, William [2 ]
机构：
[1] Univ Roma Tor Vergata, Nephrol & Dialysis Unit, Rome, Italy
[2] Univ Roma Tor Vergata, Oncohematol & Transplantat Dept, Rome, Italy
来源：
JOURNAL OF NEPHROLOGY | 2009年 / 22卷 / 01期
关键词：
Hematopoietic stem cell transplantation; Membranous nephropathy; Rituximab; ANTI-CD20; MONOCLONAL-ANTIBODY; VERSUS-HOST-DISEASE; NEPHROTIC SYNDROME;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Membranous nephropathy (MN) post allogeneic hematopoietic stem cell transplantation (HSCT) is a rare complication with few long-term outcome data. We describe the clinical course and outcome of an adult female patient who developed MN after allogeneic HSCT for follicular non-Hodgkin's lymphoma. MN was treated with methylprednisolone as first-line therapy, then she was changed to rituximab for a relapse. After treatment with rituximab, we observed a progressive decrease of proteinuria and normalization of serum albumin. Seven months after treatment, she remains in remission. No adverse reactions to rituximab were observed throughout follow-up.
引用
收藏
页码：160 / 163
页数：4
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