Rituximab in post allogeneic hematopoietic stem cell transplantation membranous nephropathy: a case report

被引：1

作者：

Vischini, Gisella ^{[1
]}

Cudillo, Laura ^{[2
]}

Ferrannini, Michele ^{[1
]}

Di Daniele, Nicola ^{[1
]}

Cerretti, Raffaella ^{[2
]}

Arcese, William ^{[2
]}

机构：

[1] Univ Roma Tor Vergata, Nephrol & Dialysis Unit, Rome, Italy

[2] Univ Roma Tor Vergata, Oncohematol & Transplantat Dept, Rome, Italy

来源：

JOURNAL OF NEPHROLOGY | 2009年 / 22卷 / 01期

关键词：

Hematopoietic stem cell transplantation; Membranous nephropathy; Rituximab; ANTI-CD20; MONOCLONAL-ANTIBODY; VERSUS-HOST-DISEASE; NEPHROTIC SYNDROME;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Membranous nephropathy (MN) post allogeneic hematopoietic stem cell transplantation (HSCT) is a rare complication with few long-term outcome data. We describe the clinical course and outcome of an adult female patient who developed MN after allogeneic HSCT for follicular non-Hodgkin's lymphoma. MN was treated with methylprednisolone as first-line therapy, then she was changed to rituximab for a relapse. After treatment with rituximab, we observed a progressive decrease of proteinuria and normalization of serum albumin. Seven months after treatment, she remains in remission. No adverse reactions to rituximab were observed throughout follow-up.

引用

页码：160 / 163

页数：4

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