Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones

被引：19

作者：

Thadkapally, Srinivas ^{[1
]}

Kunjachan, Athira C. ^{[1
]}

Menon, Rajeev S. ^{[1
]}

机构：

[1] CSIR Indian Inst Chem Technol, Med Chem & Pharmacol Div, Hyderabad 500007, Andhra Pradesh, India

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 12卷

关键词：

allenes; chromenes; cyclocondenzation; sulfones; vinylic substitution; 3-ALKYL ALLENOATES; EFFICIENT; CHROMENES; SALICYLALDEHYDES; CONSTRUCTION; 2H-CHROMENES; CYCLIZATION; METATHESIS; 1,2-DIONES; DISCOVERY;

D O I：

10.3762/bjoc.12.3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cesium carbonate-mediated reaction of 2-bromoallyl sulfones and ortho-hydroxychalcones furnished 3-arylsulfonyl-4-Hchromene derivatives in 58-67% yield (18 examples). 2-Bromoallyl sulfones functioned as synthetic surrogates for allenyl sulfones in the reaction.

引用

页码：16 / 21

页数：6

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