Direct transition metal-free C-S bond formation: synthesis of 2-aminobenzothiazole derivatives via base-mediated approach

被引：20
|
作者：
Wang, Rui [1 ]
Chen, Zhi [2 ]
Yue, Liang [1 ]
Pan, Wei [1 ]
Zhao, Jun-Jie [1 ]
机构：
[1] Chongqing Univ Technol, Sch Pharm & Bioengn, Chongqing 400054, Peoples R China
[2] Chongqing Univ Technol, Sch Chem Engn, Chongqing 400054, Peoples R China
来源：
TETRAHEDRON LETTERS | 2012年 / 53卷 / 34期
基金：
中国国家自然科学基金;
关键词：
2-Aminobenzothiazoles; Transition metal-free; Base; DABCO; S-Arylation; CATALYZED INTRAMOLECULAR CYCLIZATION; UNSYMMETRICAL THIOUREAS; BENZOTHIAZOLES; CONVERSION; THIOFORMANILIDES; ACID;
D O I：
10.1016/j.tetlet.2012.06.034
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A general, efficient, and more practical protocol for the base-mediated intermolecular or intramolecular S-arylation leading to the 2-aminobenzothiazole derivatives is reported. Remarkably, all reactions were carried out under transition-metal-free conditions with good to excellent yields, rendering the methodology presented herein highly valuable from both environmental and economic points of view. (C) 2012 Elsevier Ltd. All rights reserved.
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页码：4529 / 4531
页数：3
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