The past decade has seen a tremendous explosion of new information on the genetics of a variety of dementing disorders. This article focuses on seven of the most prominent examples of dementing disorders for which genes have been identified. The clinical, epidemiologic, and molecular genetic findings of these disorders are summarized. The goal is to bring together a succinct description of the latest genetic findings in these important disorders so that practitioners can more effectively diagnose and manage these conditions in their patients.
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Karolinska Inst, ARC, Stockholm, Sweden
Stockholm Univ, S-10691 Stockholm, SwedenKarolinska Inst, ARC, Stockholm, Sweden
Ferencz, Beata
Gerritsen, Lotte
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VU Med Ctr Amsterdam, Dept Psychiat, Stockholm, Sweden
Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, SwedenKarolinska Inst, ARC, Stockholm, Sweden
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Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R ChinaCent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R China
Jiang, Yaling
Jiao, Bin
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Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R China
Cent South Univ, Natl Clin Res Ctr Geriatr Disorders, Changsha, Peoples R China
Cent South Univ, Key Lab Hunan Prov Neurodegenerat Disorders, Changsha, Peoples R ChinaCent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R China
Jiao, Bin
Xiao, Xuewen
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Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R ChinaCent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R China
Xiao, Xuewen
Shen, Lu
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Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R China
Cent South Univ, Natl Clin Res Ctr Geriatr Disorders, Changsha, Peoples R China
Cent South Univ, Key Lab Hunan Prov Neurodegenerat Disorders, Changsha, Peoples R China
Key Lab Organ Injury Aging & Regenerat Med Hunan, Changsha, Peoples R ChinaCent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Peoples R China
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Section of Neuroscience, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Viale Pieraccini 6Section of Neuroscience, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Viale Pieraccini 6
Nacmias B.
Berti V.
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Nuclear Medicine Unit, Department of Biomedical, Experimental and Clinical Sciences, Viale Morgagni 50Section of Neuroscience, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Viale Pieraccini 6
Berti V.
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Piaceri I.
Sorbi S.
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Section of Neuroscience, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Viale Pieraccini 6Section of Neuroscience, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Viale Pieraccini 6
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Erasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Erasmus MC, Alzheimerctr Zuidwest Nederland, POB 2040, NL-3000 CA Rotterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Vergouw, Leonie J. M.
van Steenoven, Inger
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Vrije Univ Amsterdam Med Ctr, Dept Neurol, Amsterdam, Netherlands
Vrije Univ Amsterdam Med Ctr, Alzheimerctr, Amsterdam Neurosci, Amsterdam, Netherlands
POB 7057, NL-1007 MB Amsterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
van Steenoven, Inger
van de Berg, Wilma D. J.
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Vrije Univ Amsterdam Med Ctr, Dept Anat & Neurosci, Sect Clin Neuroanat, Amsterdam Neurosci, Amsterdam, Netherlands
POB 7057, NL-1007 MB Amsterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
van de Berg, Wilma D. J.
Teunissen, Charlotte E.
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Vrije Univ Amsterdam Med Ctr, Dept Clin Chem, Amsterdam Neurosci, Amsterdam, Netherlands
POB 7057, NL-1007 MB Amsterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Teunissen, Charlotte E.
van Swieten, John C.
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机构:
Erasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Erasmus MC, Alzheimerctr Zuidwest Nederland, POB 2040, NL-3000 CA Rotterdam, Netherlands
POB 2040, NL-3000 CA Rotterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
van Swieten, John C.
Bonifati, Vincenzo
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机构:
Erasmus MC, Dept Clin Genet, Rotterdam, Netherlands
POB 2040, NL-3000 CA Rotterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Bonifati, Vincenzo
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Lemstra, Afina W.
de Jong, Frank Jan
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机构:
Erasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Erasmus MC, Alzheimerctr Zuidwest Nederland, POB 2040, NL-3000 CA Rotterdam, Netherlands
POB 2040, NL-3000 CA Rotterdam, NetherlandsErasmus MC, Dept Neurol, POB 2040, NL-3000 CA Rotterdam, Netherlands