Intraosseous Delivery of Lentiviral Virus Acts as a Therapeutic Strategy for In Vivo Gene Therapy of Hemophilia

被引:0
|
作者
Wang, Xuefeng [1 ]
Sign, Swati [1 ]
Kiem, Hans-Peter [2 ]
Rawlings, David J. [1 ]
Miao, Carol H. [1 ]
机构
[1] Seattle Childrens Res Inst, Seattle, WA USA
[2] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
601
引用
收藏
页码:278 / 278
页数:1
相关论文
共 50 条
  • [31] Gene therapy for hemophilia A: Production of therapeutic levels of human factor VIII in vivo in mice
    Dwarki, V. J.
    Belloni, P.
    Nijjar, T.
    Smith, J.
    Proceedings of the National Academy of Sciences of the United States of America, 92 (04):
  • [32] Enhancing therapeutic efficacy of in vivo platelet-targeted gene therapy in hemophilia A mice
    Wang, Xuefeng
    Fu, Richard Y.
    Li, Chong
    Chen, Chun-Yu
    Firrman, Jenni
    Konkle, Barbara A.
    Zhang, Junping
    Li, Lei
    Xiao, Weidong
    Poncz, Mortimer
    Miao, Carol H.
    BLOOD ADVANCES, 2020, 4 (22) : 5722 - 5734
  • [33] DIRECT INTRAVENOUS DELIVERY OF THE HUMAN ADA GENE BY LENTIVIRAL VECTORS FOR IN VIVO ENZYME REPLACEMENT THERAPY
    Carbonaro-Sarracino, D. A.
    Lee, C. C. I.
    Jin, X.
    Tarantal, A. F.
    Kohn, D. B.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 : 132 - 132
  • [34] In Vivo HSC Gene Therapy of Hemophilia A in Mice
    Wang, Hongjie
    Gil, Sucheol
    Doering, Christopher
    Lieber, Andre
    MOLECULAR THERAPY, 2020, 28 (04) : 126 - 127
  • [35] Gene therapy:: In vivo gene delivery
    Verma, IM
    FASEB JOURNAL, 1999, 13 (07): : A1591 - A1591
  • [36] Optimization of lentiviral gene delivery to the retinal pigment epithelium in vivo
    Haire, SE
    Elder, IA
    Saban, DR
    Janssen, JJ
    Timmers, AMM
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 : U89 - U89
  • [37] Suicide gene therapy of hepatocellular carcinoma and delivery procedure and route of therapeutic gene in vivo
    Xiao-Yi Sun
    Zai-De Wu
    Jun-Bo Hu the Department of Surgery
    Hepatobiliary & Pancreatic Diseases International, 2002, (03) : 373 - 377
  • [38] Lentiviral vectors for in vivo gene therapy of metachromatic leukodystrophy
    Consiglio, A
    Dolcetta, D
    Follenzi, A
    Luca, T
    Marchesini, S
    Gritti, A
    Vescovi, A
    Naldini, L
    Bordignon, C
    JOURNAL OF NEUROCHEMISTRY, 2003, 87 : 5 - 5
  • [39] In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors
    Consiglio, A
    Follenzi, A
    Dolcetta, D
    Marchesini, S
    Orlacchio, A
    Bordignon, C
    Naldini, L
    FASEB JOURNAL, 2003, 17 (04): : A685 - A685
  • [40] Transduction of modified factor VIII gene improves lentiviral gene therapy efficacy for hemophilia A
    Gong, Jie
    Chung, Tsai-Hua
    Zheng, Jie
    Zheng, Huyong
    Chang, Lung-Ji
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 297 (06)