Sinulaflexiolide P, A Cembrane-Type Diterpenoid from Bornean Soft Coral Sinularia flexibilis

被引：7

作者：

Phan, Chin-Soon ^{[1
]}

Yee, Chun-Sieng ^{[1
]}

Vairappan, Charles Santhanaraju ^{[1
]}

Ishii, Takahiro ^{[2
]}

Kamada, Takashi ^{[3
]}

机构：

[1] Univ Malaysia Sabah, Inst Trop Biol & Conservat, Kota Kinabalu 88400, Sabah, Malaysia

[2] Univ Ryukyus, Fac Agr, Dept Biosci & Biotechnol, 1 Senbaru, Nishihara, Okinawa 9030213, Japan

[3] Shizuoka Inst Sci & Technol, Fac Sci & Technol, Dept Mat & Life Sci, 2200-2 Toyosawa, Shizuoka 4378555, Japan

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2019年 / 55卷 / 02期

关键词：

Sinularia flexibilis; soft coral; diterpenoid; cembrane; antifungal; SARCOPHYTON-TROCHELIOPHORUM; SESQUITERPENOIDS; TERPENOIDS;

D O I：

10.1007/s10600-019-02668-w

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new cembrane-type diterpenoid, sinulaflexiolide P (1), along with three known derivatives: sinulaflexiolide H (2), 11-epi-sinulariolide acetate (3), and (1S*,3S*,4S*,7E,11E)-3,4-epoxy-13-oxo-3,7,11,15-cembratriene (4), was isolated from a population of Bornean soft coral Sinularia flexibilis. The structures of these metabolites were elucidated based on spectroscopic data including NMR and HR-ESI-MS. In addition, these compounds were tested against six strains of marine fungi.

引用

页码：285 / 288

页数：4

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