Experimental and Theoretical Investigation of the Phase Behavior of Naproxen in Supercritical CO2

被引：28

作者：

Tuerk, Michael ^{[1
]}

Kraska, Thomas ^{[2
]}

机构：

[1] Univ Karlsruhe TH, Inst Tech Thermodynam & Kaltetech, D-76131 Karlsruhe, Germany

[2] Univ Cologne, Inst Phys Chem, D-50939 Cologne, Germany

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2009年 / 54卷 / 05期

关键词：

RAPID EXPANSION; SOLUBILITY; FLUIDS; DRUGS; MICRONIZATION; REARRANGEMENT; EQUILIBRIA; PARTICLES; PRESSURE; SOLIDS;

D O I：

10.1021/je800920d

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

New experimental solubility data of Naproxen in supercritical CO2 for (313 to 353) K and pressures ranging from (15 to 40) MPa are presented. This covers the range where processes with supercritical fluids such as Rapid Expansion from Supercritical Fluids are typically performed. In addition, the solid-liquid-gas equilibrium line for the CO2 + Naproxen system was determined from (0.1 to 30) MPa. The solubility data are correlated by three different methods: two methods for the density-solubility correlation and one method for the pressure-solubility correlation. Different literature data and predictions of the sublimation pressure of Naproxen, which are required for the solubility correlation, are compared.

引用

页码：1592 / 1597

页数：6

共 50 条

[21] Phase behavior of lemon and bergamot peel oils in supercritical CO2
Franceschi, E
Grings, MB
Frizzo, CD
Oliveira, JV
Dariva, C
FLUID PHASE EQUILIBRIA, 2004, 226 : 1 - 8
[22] Phase behavior of arbutin/ethanol/supercritical CO2 at elevated pressures
Han, Chang-Nam
Kang, Choon-Hyoung
KOREAN JOURNAL OF CHEMICAL ENGINEERING, 2017, 34 (06) : 1781 - 1785
[23] Experimental and theoretical study of phase behavior for live oil during CO2 EOR process
Kia, Ali
Sarlak, Amir Reza
Tabari, Amir Hossein
Afkan, Saeed Bazr
Keshavarz, Marzyeh
Maddah, Heydar
PETROLEUM SCIENCE AND TECHNOLOGY, 2017, 35 (05) : 451 - 456
[24] Experimental investigation on heat transfer of an impinging jet of supercritical CO2 and comparison with liquid and gaseous CO2
Kim, Seon Ho
Park, Seong-Hyeok
Park, Hee Seung
Hsu, Wei -Ting
Cho, Hyung Hee
INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER, 2024, 153
[25] Experimental and numerical investigation of supercritical CO2 test loop transient behavior near the critical point operation
Bae, Seong Jun
Ahn, Yoonhan
Lee, Jekyoung
Kim, Seong Gu
Baik, Seungjoon
Lee, Jeong Ik
APPLIED THERMAL ENGINEERING, 2016, 99 : 572 - 582
[26] Experimental investigation of CO2 thermosyphon flow and heat transfer in the supercritical region
Chen, Lin
Deng, Bi-Li
Zhang, Xin-Rong
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 2013, 64 : 202 - 211
[27] Experimental and thermodynamic investigation of gemifloxacin solubility in supercritical CO2 for the production of nanoparticles
Arabgol, Fatemeh
Amani, Mitra
Ardestani, Nedasadat Saadati
Sajadian, Seyed Ali
JOURNAL OF SUPERCRITICAL FLUIDS, 2024, 206
[28] Experimental investigation on flow characteristics of supercritical CO2 in a helically coiled tube
Wang, Shuxiang
Zhang, Wei
Xu, Jinliang
FRONTIERS OF GREEN BUILDING, MATERIALS AND CIVIL ENGINEERING III, PTS 1-3, 2013, 368-370 : 631 - 635
[29] An experimental investigation of supercritical CO2 accidental release from a pressurized pipeline
Li, Kang
Zhou, Xuejin
Tu, Ran
Xie, Qiyuan
Yi, Jianxin
Jiang, Xi
JOURNAL OF SUPERCRITICAL FLUIDS, 2016, 107 : 298 - 306
[30] Numerical Investigation of the Flow Behavior Inside a Supercritical CO2 Centrifugal Compressor
Ameli, Alireza
Turunen-Saaresti, Teemu
Backman, Jari
JOURNAL OF ENGINEERING FOR GAS TURBINES AND POWER-TRANSACTIONS OF THE ASME, 2018, 140 (12):

← 1 2 3 4 5 →