Experimental and Theoretical Investigation of the Phase Behavior of Naproxen in Supercritical CO2

被引：28
|
作者：
Tuerk, Michael [1 ]
Kraska, Thomas [2 ]
机构：
[1] Univ Karlsruhe TH, Inst Tech Thermodynam & Kaltetech, D-76131 Karlsruhe, Germany
[2] Univ Cologne, Inst Phys Chem, D-50939 Cologne, Germany
来源：
JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2009年 / 54卷 / 05期
关键词：
RAPID EXPANSION; SOLUBILITY; FLUIDS; DRUGS; MICRONIZATION; REARRANGEMENT; EQUILIBRIA; PARTICLES; PRESSURE; SOLIDS;
D O I：
10.1021/je800920d
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
New experimental solubility data of Naproxen in supercritical CO2 for (313 to 353) K and pressures ranging from (15 to 40) MPa are presented. This covers the range where processes with supercritical fluids such as Rapid Expansion from Supercritical Fluids are typically performed. In addition, the solid-liquid-gas equilibrium line for the CO2 + Naproxen system was determined from (0.1 to 30) MPa. The solubility data are correlated by three different methods: two methods for the density-solubility correlation and one method for the pressure-solubility correlation. Different literature data and predictions of the sublimation pressure of Naproxen, which are required for the solubility correlation, are compared.
引用
收藏
页码：1592 / 1597
页数：6
相关论文
共 50 条
  • [1] Processing naproxen with supercritical CO2
    Montes, A.
    Bendel, A.
    Kuerti, R.
    Gordillo, M. D.
    Pereyra, C.
    Martinez de la Ossa, E. J.
    JOURNAL OF SUPERCRITICAL FLUIDS, 2013, 75 : 21 - 29
  • [2] Experimental Investigation on the Behavior of Supercritical CO2 during Reservoir Depressurization
    Li, Rong
    Jiang, Peixue
    He, Di
    Chen, Xue
    Xu, Ruina
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 51 (15) : 8869 - 8876
  • [3] An experimental investigation on phase behavior of a light oil and CO2
    Elias, A., Jr.
    Trevisan, Osvair V.
    JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING, 2016, 145 : 22 - 33
  • [4] Experimental and theoretical investigation on permeability evolution of fractures in anthracite with supercritical CO2 immersion
    Wei, Jie
    Chen, Yuedu
    Liang, Weiguo
    INTERNATIONAL JOURNAL OF ROCK MECHANICS AND MINING SCIENCES, 2024, 174
  • [5] Experimental and theoretical analysis of the diffusion behavior of chromium(III) acetylacetonate in supercritical CO2
    Cordeiro, Joana
    Magalhaes, Ana L.
    Valente, Anabela A.
    Silva, Carlos M.
    JOURNAL OF SUPERCRITICAL FLUIDS, 2016, 118 : 153 - 162
  • [6] Foaming of polymers with supercritical CO2:: An experimental and theoretical study
    Tsivintzelis, Ioannis
    Angelopoulou, Anastasia G.
    Panayiotou, Costas
    POLYMER, 2007, 48 (20) : 5928 - 5939
  • [7] Experimental investigation on abrasive supercritical CO2 jet perforation
    Wang Haizhu
    Li Gensheng
    He Zhenguo
    Tian Shouceng
    Wang Meng
    Yang Bing
    Lu Qun
    Weng Lianze
    JOURNAL OF CO2 UTILIZATION, 2018, 28 : 59 - 65
  • [8] Experimental determination and modeling of the phase behavior for the selective oxidation of benzyl alcohol in supercritical CO2
    Tsivintzelis, Ioannis
    Beier, Matthias Josef
    Grunwaldt, Jan-Dierk
    Baiker, Alfons
    Kontogeorgis, Georgios M.
    FLUID PHASE EQUILIBRIA, 2011, 302 (1-2) : 83 - 92
  • [9] Experimental investigation of the mechanism of supercritical CO2 interaction with tight sandstone
    Peng, Huan
    Yang, Jian
    Peng, Junliang
    Pu, Junhong
    Liu, Qiang
    Su, Jun
    Liu, Jin
    FRONTIERS IN ENERGY RESEARCH, 2022, 10
  • [10] An Experimental Investigation of Supercritical Methane Injection Characteristics in a CO2 Environment
    Ghorpade, Ritesh
    Kim, Gihun
    Manikantachari , K. R. V.
    Weiner, Joshua
    Banuti, Daniel T. T.
    Vasu, Subith
    JOURNAL OF ENGINEERING FOR GAS TURBINES AND POWER-TRANSACTIONS OF THE ASME, 2023, 145 (03):
12345