Convenient synthesis of some 4′-methylthio-containing aryl and arylfuryl pyrazolines and their antimicrobial activity studies

被引：8
|
作者：
Holla, Bantwal Shivarama [1 ]
Mahalinga, Manjathuru [1 ]
Ashok, Mithun [1 ]
Karegoudar, Prakash [1 ]
机构：
[1] Mangalore Univ, Dept Chem, Mangalagangothri 574199, India
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2006年 / 181卷 / 06期
关键词：
4-cetylthioanisole; aryfuryl aldehydes; antimcrobial; propenones; pyrazolines;
D O I：
10.1080/10426500500328939
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The condensation of 4-acetylthioanisole with different aryl and aryfuryl aldehydes under aldol conditions affords alpha, beta-unsaturated ketones (propenones), which undergo a facile and clean cyclization with hydrazines to give pyrazolines (4-6) in quantitative yields. The structures of newly synthesized compounds have been confirmed on the basis of spectral studies. All newly synthesized compounds were tested for their antibacterial and antifungal activity.
引用
收藏
页码：1427 / 1436
页数：10
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