Convenient synthesis of some 4′-methylthio-containing aryl and arylfuryl pyrazolines and their antimicrobial activity studies

被引：8
|
作者：
Holla, Bantwal Shivarama [1 ]
Mahalinga, Manjathuru [1 ]
Ashok, Mithun [1 ]
Karegoudar, Prakash [1 ]
机构：
[1] Mangalore Univ, Dept Chem, Mangalagangothri 574199, India
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2006年 / 181卷 / 06期
关键词：
4-cetylthioanisole; aryfuryl aldehydes; antimcrobial; propenones; pyrazolines;
D O I：
10.1080/10426500500328939
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The condensation of 4-acetylthioanisole with different aryl and aryfuryl aldehydes under aldol conditions affords alpha, beta-unsaturated ketones (propenones), which undergo a facile and clean cyclization with hydrazines to give pyrazolines (4-6) in quantitative yields. The structures of newly synthesized compounds have been confirmed on the basis of spectral studies. All newly synthesized compounds were tested for their antibacterial and antifungal activity.
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页码：1427 / 1436
页数：10
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