Caffeine consumption and miscarriage: a prospective cohort study

被引:20
|
作者
Pollack, Anna Z. [3 ]
Louis, Germaine M. Buck [1 ]
Sundaram, Rajeshwari [2 ]
Lum, Kirsten J. [2 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Epidemiol Branch, Div Epidemiol Stat & Prevent Res, Rockville, MD 20852 USA
[2] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Biostat & Bioinformat Branch, Div Epidemiol Stat & Prevent Res, Rockville, MD 20852 USA
[3] Johns Hopkins Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
关键词
SPONTANEOUS-ABORTION; PREGNANCY; RISK; REGRESSION;
D O I
10.1016/j.fertnstert.2009.07.992
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Caffeine consumption has been equivocally associated with miscarriage, despite an absence of prospective longitudinal measurement of caffeine intake during sensitive windows of human development. In response to this critical data gap, we analyzed daily caffeine consumption while attempting pregnancy through 12 menstrual cycles at risk for pregnancy and found that caffeine consumption did not increase the risk or hazard of miscarriage, even after adjusting for relevant covariates. (Fertil Steril(R) 2010;93:304-6. (C)2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:304 / 306
页数:3
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