Pathogen recognition by innate immunity and its signaling

被引：182

作者：

Akira, Shizuo ^{[1
]}

机构：

[1] Osaka Univ, Host Def Lab, WPI Immunol Frontier Res Ctr, Suita, Osaka 5650871, Japan

来源：

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES | 2009年 / 85卷 / 04期

关键词：

Toll-like receptor; innate immunity; pathogen; interferon; signaling; cytokine; NF-KAPPA-B; DOUBLE-STRANDED-RNA; DOMAIN-CONTAINING ADAPTER; IFN-REGULATORY FACTOR-3; TANK-BINDING KINASE-1; RIG-I; CUTTING EDGE; TRANSCRIPTION FACTORS; DIFFERENTIAL ROLES; ACTIVATION;

D O I：

10.2183/pjab.85.143

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mammalian immune response can be divided into innate and acquired immunity. Furthermore, much evidence has demonstrated that activation of innate immunity is a prerequisite to induction of acquired immunity. This paradigm shift has changed our thinking on the pathogenesis and treatment of infections, immune diseases, allergy, and cancers.

引用

页码：143 / 156

页数：14

共 50 条

[41] Pathogen recognition and STING signaling
Barber, Glen
CYTOKINE, 2015, 76 (01) : 61 - 61
[42] Pathogen perception and signaling in plant immunity
Dodds, Peter N.
Chen, Jian
Outram, Megan A.
PLANT CELL, 2024, 36 (05): : 1465 - 1481
[43] INNATE IMMUNITY Pathogen and xenobiotic sensing - back to basics
Cunha, Andreia
NATURE REVIEWS IMMUNOLOGY, 2012, 12 (06) : 400 - 401
[44] Role of Ubiquitination in Plant Innate Immunity and Pathogen Virulence
Gautam Shirsekar
Liangying Dai
Yajun Hu
Xuejun Wang
Lirong Zeng
Guo-Liang Wang
Journal of Plant Biology, 2010, 53 : 10 - 18
[45] Pathogen subversion of cell-intrinsic innate immunity
Roy, Craig R.
Mocarski, Edward S.
NATURE IMMUNOLOGY, 2007, 8 (11) : 1179 - 1187
[46] Drosophila innate immunity:: A genomic view of pathogen defense
Jasper, H
Bohmann, D
MOLECULAR CELL, 2002, 10 (05) : 967 - 969
[47] Innate immunity decreases pathogen diversity during infection
Kagan, Jonathan C.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 120 (40)
[48] Xenophagy in innate immunity: A battle between host and pathogen
Wang, Zhenhui
Li, Chenghua
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2020, 109
[49] Phagocytosis, innate immunity, and host-pathogen specificity
Henneke, P
Golenbock, DT
JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 199 (01): : 1 - 4
[50] Role of Ubiquitination in Plant Innate Immunity and Pathogen Virulence
Shirsekar, Gautam
Dai, Liangying
Hu, Yajun
Wang, Xuejun
Zeng, Lirong
Wang, Guo-Liang
JOURNAL OF PLANT BIOLOGY, 2010, 53 (01) : 10 - 18

← 1 2 3 4 5 →