Nickel(II) phosphine-catalysed hydrodehalogenation of aryl halides under mild ambient conditions

被引：3
|
作者：
Guek, Sebastian Jun Kai [1 ]
Ji, Li [2 ]
Loke, James Wen Liang [2 ]
Koh, Hwee Ling [1 ]
Fan, Wai Yip [2 ]
机构：
[1] Natl Univ Singapore, Dept Pharm, 18 Sci Dr 4, Singapore 117543, Singapore
[2] Natl Univ Singapore, Dept Chem, 3 Sci Dr 3, Singapore 117543, Singapore
来源：
MOLECULAR CATALYSIS | 2022年 / 524卷
关键词：
Hydrodehalogenation; Nickel phosphines; Aryl halides; Polyfluorinated arenes; Borohydride; POLYCHLORINATED-BIPHENYLS; COMPLEXES; HYDRODEFLUORINATION; REDUCTION;
D O I：
10.1016/j.mcat.2022.112310
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A convenient and low-cost hydrodehalogenation process catalysed by air-stable nickel(II) complexes containing bidentate phosphine ligands has been developed under ambient conditions with sodium borohydride acting as the reducing agent and hydrogen atom source. High conversions of aryl halides, including polyfluorinated substrates, into their hydrogenated counterparts have been achieved in dimethylformamide (DMF) and to a moderate extent, in DMF/isopropanol (10:90% v/v) solvent mixture. A mechanism has been proposed to account for the experimental data.
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页数：8
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