Alkylthiolation of Aryl Halides under Electrochemical Conditions

被引：0

作者：

Fan, Yingsibing ^{[1
]}

Zhang, Tan ^{[1
]}

Wu, Mengyun ^{[1
]}

Liu, Ping ^{[1
]}

Sun, Peipei ^{[1
]}

机构：

[1] Nanjing Normal Univ, Jiangsu Collaborat Innovat Ctr Biomed Funct Mat, Sch Chem & Mat Sci, Jiangsu Prov Key Lab Mat Cycle Proc & Pollut Contr, Nanjing 210023, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 23期

基金：

中国国家自然科学基金;

关键词：

CATALYZED C-S; BOND FORMATION; PHOTOREDOX CATALYSIS; RADICAL BORYLATION; ARYLBORONIC ACIDS; METAL; ARYLATION; HETEROARYL; GENERATION; ACCESS;

D O I：

10.1021/acs.joc.4c02566

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An electrochemical protocol for the alkylthiolation of aryl halides was developed. By using dialkyl disulfides as the alkylthio sources, Mg plate as the sacrificial anode and graphite felt (GF) as the cathode, a series of aryl sulfides were obtained in moderate to good yields. The approach was also suitable for the synthesis of aryl selenides. This method has the features such as simple reaction conditions and good functional group compatibility, which makes it have a good application prospect in organic synthesis and drug synthesis.

引用

页码：17744 / 17751

页数：8

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