Recent advancements in surface-enhanced laser desorption/ionization-time of flight-mass spectrometry

被引：78
|
作者：
Merchant, M [1 ]
Weinberger, SR [1 ]
机构：
[1] Ciphergen Biosyst Inc, Palo Alto, CA 94306 USA
来源：
ELECTROPHORESIS | 2000年 / 21卷 / 06期
关键词：
surface-enhanced laser desorption; ionization; review;
D O I：
10.1002/(SICI)1522-2683(20000401)21:6<1164::AID-ELPS1164>3.3.CO;2-S
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The overall history and recent advances in surface enhanced laser desorption/ionization-time of flight-mass spectrometry (SELDI-TOF-MS) technology is reviewed herein. Fundamentals of SELDI-TOF analysis are presented while drawing comparisons with other laser-based mass spectrometry techniques. The application of SELDI-TOF-MS to functional genomics and biomarker discovery is discussed and exemplified by elucidating a biomarker candidate for prostatic carcinoma. Finally, a short discussion regarding future SELDI requirements and developments is supplied.
引用
收藏
页码：1164 / 1177
页数：14
相关论文
共 50 条
  • [31] Protein alkylation in the presence/absence of thiourea in proteome analysis: A matrix assisted laser desorption/ionization-time of flight-mass spectrometry investigation
    Galvani, M
    Rovatti, L
    Hamdan, M
    Herbert, B
    Righetti, PG
    ELECTROPHORESIS, 2001, 22 (10) : 2066 - 2074
  • [32] Matrix of 3,4-Diaminobenzophenone for Analysis of Phospholipids by Matrix-Assisted Laser Desorption/Ionization-Time of Flight-Mass Spectrometry
    Miao Nan
    Zhang Yu
    Zhang Jian-Ye
    Zou Han-Fa
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2011, 39 (05) : 605 - 610
  • [33] Proteomics profiling of urine with surface enhanced laser desorption/ionization time of flight mass spectrometry
    Han Roelofsen
    Gloria Alvarez-Llamas
    Marianne Schepers
    Karloes Landman
    Roel J Vonk
    Proteome Science, 5
  • [34] Proteomics profiling of urine with surface enhanced laser desorption/ionization time of flight mass spectrometry
    Roelofsen, Han
    Alvarez-Llamas, Gloria
    Schepers, Marianne
    Landman, Karloes
    Vonk, Roel J.
    PROTEOME SCIENCE, 2007, 5 (1)
  • [35] Enzymatic reaction of the immobilized enzyme on porous silicon studied by matrix-assisted laser desorption/ionization-time of flight-mass spectrometry
    Xu, SY
    Pan, CS
    Hu, LG
    Zhang, Y
    Guo, Z
    Li, X
    Zou, HF
    ELECTROPHORESIS, 2004, 25 (21-22) : 3669 - 3676
  • [36] Composition, structure and function from endopeptidease of Aplysia egg analyzed with matrix assisted laser desorption ionization-time of flight-mass spectrometry
    Huang He-Qing
    Lu Yong-Jin
    Lin Qing-Mei
    Zhuo Hui-Qin
    Huang Hui-Ying
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2007, 35 (08) : 1105 - 1110
  • [37] Stability and splitting produces revealed by matrix-assisted laser desorption ionization-time of flight-mass Spectrometry in human serum transferrin
    Zhuo Hui-Qin
    Jin Hong-Wei
    Huang He-Qing
    Huang Hui-Ying
    Cai ZongWei
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2007, 35 (06) : 791 - 796
  • [38] Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Clinical Microbiology
    Patel, Robin
    CLINICAL INFECTIOUS DISEASES, 2013, 57 (04) : 564 - 572
  • [39] Identification of Molds by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
    Sanguinetti, Maurizio
    Posteraro, Brunella
    JOURNAL OF CLINICAL MICROBIOLOGY, 2017, 55 (02) : 369 - 379
  • [40] Matrix assisted laser desorption ionization-time of flight mass spectrometry analysis of hyaluronan oligosaccharides
    Sakai, Shinobu
    Hirano, Kana
    Toyoda, Hidenao
    Linhardt, Robert J.
    Toida, Toshihiko
    ANALYTICA CHIMICA ACTA, 2007, 593 (02) : 207 - 213
12345