Spontaneous ocular autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen

被引:0
|
作者
Horai, Reiko [1 ]
Silver, Phyllis B. [1 ]
Chen, Jun [1 ]
Zarate-Blades, Carlos [1 ]
Chong, Wai Po [1 ]
Zhou, Ru [1 ]
Jittayasothorn, Yingyos [1 ]
Sonia Nguyen [1 ]
Chan, Chi-Chao [1 ]
Caspi, Rachel R. [1 ]
机构
[1] NEI, Immunol Lab, NIH, Bethesda, MD USA
关键词
746 uveitis-clinical/animal model; 432 autoimmune disease; 557; inflammation;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
2499
引用
收藏
页数:3
相关论文
共 50 条
  • [31] SPREADING OF T-CELL AUTOIMMUNITY TO CRYPTIC DETERMINANTS OF AN AUTOANTIGEN
    LEHMANN, PV
    FORSTHUBER, T
    MILLER, A
    SERCARZ, EE
    NATURE, 1992, 358 (6382) : 155 - 157
  • [32] TOLERANCE INDUCTION IN DOUBLE SPECIFIC T-CELL RECEPTOR TRANSGENIC MICE VARIES WITH ANTIGEN
    PIRCHER, H
    BURKI, K
    LANG, R
    HENGARTNER, H
    ZINKERNAGEL, RM
    NATURE, 1989, 342 (6249) : 559 - 561
  • [33] Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice
    Guan, Yangtai
    Shindler, Kenneth S.
    Rostami, A. M.
    ANNALS OF NEUROLOGY, 2006, 60 : S36 - S36
  • [34] Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice
    Guan, Yangtai
    Shindler, Kenneth S.
    Tabuena, Philomela
    Rostami, A. M.
    JOURNAL OF NEUROIMMUNOLOGY, 2006, 178 (1-2) : 40 - 48
  • [35] T Cell Receptor Signal Strength Controls Onset and Severity of Arthritis in Antigen (Proteoglycan Epitope)-Specific T Cell Receptor Transgenic Mice
    Olasz, Katalin
    Boldizsar, Ferenc
    Kis-Toth, Katalin
    Tarjanyi, Oktavia
    Hegyi, Akos
    van Eden, Willem
    Rauch, Tibor A.
    Mikecz, Katalin
    Glant, Tibor T.
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S911 - S911
  • [36] Disruption of T cell subset homeostasis in mice expressing a T cell specific dominant negative TGF-β II receptor
    Lucas, PJ
    Kim, SJ
    Melby, S
    Gress, RE
    FASEB JOURNAL, 2000, 14 (06): : A1225 - A1225
  • [37] Kinetics of ocular pathology and immune profile of double transgenic mice expressing a foreign antigen in their lens and a receptor against it on their T-cells
    Zhang, MF
    Vistica, BP
    Matteson, D
    Wawrousek, EF
    Chan, CC
    Gery, I
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1999, 40 (04) : S861 - S861
  • [38] T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice
    Bettini, Matthew L.
    Bettini, Maria
    Vignali, Dario A. A.
    IMMUNOLOGY, 2012, 136 (03) : 265 - 272
  • [39] T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes
    Pauza, ME
    Dobbs, CM
    He, J
    Patterson, T
    Wagner, S
    Anobile, BS
    Bradley, BJ
    Lo, D
    Haskins, K
    DIABETES, 2004, 53 (04) : 978 - 988
  • [40] Generation of transgenic animals expressing the α and β chains of the autoreactive T-cell receptor
    E. S. Zvezdova
    Yu. Yu. Silaeva
    M. S. Vagida
    E. V. Maryukhnich
    A. V. Deikin
    T. G. Ermolkevich
    S. G. Kadulin
    E. R. Sadchikova
    I. L. Goldman
    D. B. Kazansky
    Molecular Biology, 2010, 44 : 277 - 286