Spontaneous ocular autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen

被引：0
|
作者：
Horai, Reiko [1 ]
Silver, Phyllis B. [1 ]
Chen, Jun [1 ]
Zarate-Blades, Carlos [1 ]
Chong, Wai Po [1 ]
Zhou, Ru [1 ]
Jittayasothorn, Yingyos [1 ]
Sonia Nguyen [1 ]
Chan, Chi-Chao [1 ]
Caspi, Rachel R. [1 ]
机构：
[1] NEI, Immunol Lab, NIH, Bethesda, MD USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2014年 / 55卷 / 13期
关键词：
746 uveitis-clinical/animal model; 432 autoimmune disease; 557; inflammation;
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
2499
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Transgenic Mice That Express a Myelin Basic Protein-Specific T Cell Receptor Develop Spontaneous Autoimmunity (Reprinted from Cell, vol 72, pg 551-560, 1993)
    Goverman, Joan
    Woods, Andrea
    Larson, Lisa
    Weiner, Leslie P.
    Hood, Leroy
    Zaller, Dennis M.
    JOURNAL OF IMMUNOLOGY, 2013, 190 (07): : 3018 - 3027
  • [22] Cell receptor (TCR) transgenic mice expressing autoreactive T cells to tubular antigen.
    Yamasaki, Y
    Danoff, TM
    Meyers, C
    Neilson, EG
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1996, 7 (09): : A2397 - A2397
  • [23] INHIBITION OF ABNORMAL T-CELL DEVELOPMENT AND AUTOIMMUNITY IN GLD MICE BY TRANSGENIC T-CELL RECEPTOR BETA CHAIN
    YUI, K
    BHANDOOLA, A
    RADIC, MZ
    KOMORI, S
    KATSUMATA, M
    GREENE, MI
    EUROPEAN JOURNAL OF IMMUNOLOGY, 1992, 22 (07) : 1693 - 1700
  • [24] Regulatory CD4+ T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
    Olivares-Villagómez, D
    Wang, YJ
    Lafaille, JJ
    JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 188 (10): : 1883 - 1894
  • [25] Generation and characterization of transgenic mice expressing a T-cell receptor specific for the tumour-associated antigen MDM2
    Xue, Shao-An
    Bendle, Gavin M.
    Holler, Angelika
    Stauss, Hans J.
    IMMUNOLOGY, 2008, 124 (03) : 315 - 321
  • [26] Spontaneous organ-specific Th2-mediated autoimmunity in TCR transgenic mice
    Candon, S
    McHugh, RS
    Foucras, G
    Natarajan, K
    Shevach, EM
    Margulies, DH
    JOURNAL OF IMMUNOLOGY, 2004, 172 (05): : 2917 - 2924
  • [27] Development of uveitis in a mouse model of spontaneous autoimmunity correlates with frequency of autoantigen-specific regulatory T cells
    Yin, Mianmian
    Hiam, Kamir J.
    Proekt, Irina
    Chan, Jackie
    Hu, Yongmei
    Lowell, Clifford A.
    Gould, Douglas B.
    Spitzer, Matthew
    Anderson, Mark S.
    DeFranco, Anthony L.
    JOURNAL OF IMMUNOLOGY, 2022, 208 (01):
  • [28] TRANSGENIC MICE EXPRESSING A CONSTITUTIVELY ACTIVE RETINOIC ACID RECEPTOR IN THE LENS EXHIBIT OCULAR DEFECTS
    BALKAN, W
    KLINTWORTH, GK
    BOCK, CB
    LINNEY, E
    DEVELOPMENTAL BIOLOGY, 1992, 151 (02) : 622 - 625
  • [29] Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic alpha beta T cell - Separation of autoantigen-specific and -nonspecific help
    Peng, SL
    Fatenejad, S
    Craft, J
    JOURNAL OF IMMUNOLOGY, 1996, 157 (12): : 5225 - 5230
  • [30] Impaired Activation-Induced Cell Death Promotes Spontaneous Arthritis in Antigen (Cartilage Proteoglycan)-Specific T Cell Receptor-Transgenic Mice
    Boldizsar, Ferenc
    Kis-Toth, Katalin
    Tarjanyi, Oktavia
    Olasz, Katalin
    Hegyi, Akos
    Mikecz, Katalin
    Glant, Tibor T.
    ARTHRITIS AND RHEUMATISM, 2010, 62 (10): : 2984 - 2994
12345