Spontaneous ocular autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen

被引：0
|
作者：
Horai, Reiko [1 ]
Silver, Phyllis B. [1 ]
Chen, Jun [1 ]
Zarate-Blades, Carlos [1 ]
Chong, Wai Po [1 ]
Zhou, Ru [1 ]
Jittayasothorn, Yingyos [1 ]
Sonia Nguyen [1 ]
Chan, Chi-Chao [1 ]
Caspi, Rachel R. [1 ]
机构：
[1] NEI, Immunol Lab, NIH, Bethesda, MD USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2014年 / 55卷 / 13期
关键词：
746 uveitis-clinical/animal model; 432 autoimmune disease; 557; inflammation;
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
2499
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Breakdown of immune privilege and spontaneous autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen
    Horai, Reiko
    Silver, Phyllis B.
    Chen, Jun
    Agarwal, Rajeev K.
    Chong, Wai Po
    Jittayasothorn, Yingyos
    Mattapallil, Mary J.
    Nguyen, Sonia
    Natarajan, Kannan
    Villasmil, Rafael
    Wang, Peng
    Karabekian, Zaruhi
    Lytton, Simon D.
    Chan, Chi-Chao
    Caspi, Rachel R.
    JOURNAL OF AUTOIMMUNITY, 2013, 44 : 21 - 33
  • [2] Spontaneous Ocular Autoimmunity in Mice Expressing a Transgenic T Cell Receptor Specific to Retina: A Tool to Dissect Mechanisms of Uveitis
    Horai, R.
    Chong, W. P.
    Zhou, R.
    Chen, J.
    Silver, P. B.
    Agarwal, R. K.
    Caspi, R. R.
    CURRENT MOLECULAR MEDICINE, 2015, 15 (06) : 511 - 516
  • [3] Breakdown of Immune Privilege and Spontaneous Ocular Autoimmunity in IRBP-Specific T Cell Receptor Transgenic Mice
    Horai, R.
    Silver, P. B.
    Yazdani, A. T.
    Nguyen, S.
    Mattapallil, M. J.
    Chan, C. -C.
    Caspi, R. R.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
  • [4] A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity
    McHugh, RS
    Shevach, EM
    Margulies, DH
    Natarajan, K
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2001, 31 (07) : 2094 - 2103
  • [5] Human gut commensals support development of ocular autoimmunity in retina-specific T cell receptor transgenic mice
    Zhang, Amy
    Horai, Reiko
    Jittayasothorn, Yingyos
    Badger, Jonathan H.
    Nagarajan, Vijayaraj
    Murphy, Caitlin Elizabeth
    Yuan, Wuxing
    O'hUigin, Colm
    Honda, Kenya
    Caspi, Rachel
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [6] TRANSGENIC MICE THAT EXPRESS A MYELIN BASIC PROTEIN-SPECIFIC T-CELL RECEPTOR DEVELOP SPONTANEOUS AUTOIMMUNITY
    GOVERMAN, J
    WOODS, A
    LARSON, L
    WEINER, LP
    HOOD, L
    ZALLER, DM
    CELL, 1993, 72 (04) : 551 - 560
  • [7] Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor
    Waldner, H
    Whitters, MJ
    Sobel, RA
    Collins, M
    Kuchroo, VK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (07) : 3412 - 3417
  • [8] T cell autoimmunity in Ig transgenic mice
    Shinde, S
    Gee, R
    Santulli-Marotto, S
    Bockenstedt, LK
    Clarke, SH
    Mamula, MJ
    JOURNAL OF IMMUNOLOGY, 1999, 162 (12): : 7519 - 7524
  • [9] T-CELL RESPONSIVENESS TO AN ONCOGENIC PERIPHERAL PROTEIN AND SPONTANEOUS AUTOIMMUNITY IN TRANSGENIC MICE
    GEIGER, T
    GOODING, LR
    FLAVELL, RA
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (07) : 2985 - 2989
  • [10] Autoantigen specific T-cell receptor induces organ-specific autoimmunity by escaping T-cell negative selection
    Yin, Mianmian
    Smith, Jennifer A.
    Chou, Marissa
    Chan, Jackie
    Hu, Yongmei
    Lowell, Clifford A.
    Gould, Douglas B.
    Anderson, Mark S.
    DeFranco, Anthony L.
    JOURNAL OF IMMUNOLOGY, 2022, 208 (01):
12345