The phosphoinositide-3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption

被引:0
|
作者
Gyori, D. [1 ]
Csete, D. [1 ]
Kulkarni, S. [2 ]
Benko, S. [3 ]
Mandl, P. [4 ]
Dobo-Nagy, C. [1 ]
Vanhaesebroeck, B. [5 ]
Stephens, L. [2 ]
Hawkins, P. T. [2 ]
Mocsai, A. [1 ]
机构
[1] Semmelweis Univ, Sch Med, Dept Physiol, Budapest, Hungary
[2] Babraham Inst, Cambridge, England
[3] Univ Debrecen, Dept Physiol, H-4012 Debrecen, Hungary
[4] Univ Vienna, Div Rheumatol, Vienna, Austria
[5] Barts Canc Ctr, Ctr Cell Signaling, London, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:40 / 40
页数:1
相关论文
共 50 条
  • [31] Phosphoinositide-3-kinase p110δ isoform promotes influenza pathogenicity
    Hancock, Aidan
    Boesteanu, Alina
    Chroneos, Zissis
    Turner, Martin
    Katsikis, Peter
    JOURNAL OF IMMUNOLOGY, 2014, 192
  • [32] Characterization of phosphoinositide-3-kinase (PI3K) effector requirements for PKB (Akt)/mTOR/p70S6K activation.
    Arvisais, EW
    Hou, XY
    Davis, JS
    BIOLOGY OF REPRODUCTION, 2005, : 253 - 254
  • [33] Quasi 4D-QSAR and 3D-QSAR study of the pan class I phosphoinositide-3-kinase (PI3K) inhibitors
    Safavi-Sohi, Reihaneh
    Ghasemi, Jahan B.
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (04) : 1587 - 1596
  • [34] Quasi 4D-QSAR and 3D-QSAR study of the pan class I phosphoinositide-3-kinase (PI3K) inhibitors
    Reihaneh Safavi-Sohi
    Jahan B. Ghasemi
    Medicinal Chemistry Research, 2013, 22 : 1587 - 1596
  • [35] The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL
    K Balakrishnan
    M Peluso
    M Fu
    N Y Rosin
    J A Burger
    W G Wierda
    M J Keating
    K Faia
    S O'Brien
    J L Kutok
    V Gandhi
    Leukemia, 2015, 29 : 1811 - 1822
  • [36] The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL
    Balakrishnan, K.
    Peluso, M.
    Fu, M.
    Rosin, N. Y.
    Burger, J. A.
    Wierda, W. G.
    Keating, M. J.
    Faia, K.
    O'Brien, S.
    Kutok, J. L.
    Gandhi, V.
    LEUKEMIA, 2015, 29 (09) : 1811 - 1822
  • [37] Role of the phosphoinositide-3-kinase/serin-treonin kinase (Pi3k/Akt) signaling in myocardial dystrophin expression in mice submitted to cecal ligation and puncture
    Campos Pulici, E. C.
    Celes, M. R. N.
    Figueiredo, M. J.
    Freitas, A. C. S.
    Ramos, S. G.
    VIRCHOWS ARCHIV, 2015, 467 : S106 - S107
  • [38] Structural Perturbations due to Mutation (H1047R) in Phosphoinositide-3-kinase (PI3Kα) and Its Involvement in Oncogenesis: An in Silico Insight
    Sharma, Jatin
    Bhardwaj, Vijay
    Purohit, Rituraj
    ACS OMEGA, 2019, 4 (14): : 15815 - 15823
  • [39] Discovery of new aminopyrimidine-based phosphoinositide 3-kinase beta (PI3Kβ) inhibitors with selectivity over PI3Kα
    Kim, Jinhee
    Hong, Seunghee
    Hong, Sungwoo
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (23) : 6977 - 6981
  • [40] Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption
    Zhu, Lingxin
    Tang, Yi
    Li, Xiao-Yan
    Kerk, Samuel A.
    Lyssiotis, Costas A.
    Sun, Xiaoyue
    Wang, Zijun
    Cho, Jung-Sun
    Ma, Jun
    Weiss, Stephen J.
    JOURNAL OF CELL BIOLOGY, 2023, 222 (04):