The phosphoinositide-3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption

被引：0
|
作者：
Gyori, D. [1 ]
Csete, D. [1 ]
Kulkarni, S. [2 ]
Benko, S. [3 ]
Mandl, P. [4 ]
Dobo-Nagy, C. [1 ]
Vanhaesebroeck, B. [5 ]
Stephens, L. [2 ]
Hawkins, P. T. [2 ]
Mocsai, A. [1 ]
机构：
[1] Semmelweis Univ, Sch Med, Dept Physiol, Budapest, Hungary
[2] Babraham Inst, Cambridge, England
[3] Univ Debrecen, Dept Physiol, H-4012 Debrecen, Hungary
[4] Univ Vienna, Div Rheumatol, Vienna, Austria
[5] Barts Canc Ctr, Ctr Cell Signaling, London, England
来源：
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 2014年 / 44卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：40 / 40
页数：1
相关论文
共 50 条
  • [21] Role of phosphoinositide-3-kinase (PI3K) in the nucleus of the solitary tract (NTS) in the modulation of baroreceptor reflex function in the hypertensive rat
    Zubcevic, Jasenka
    Polson, Jaimie W.
    Kasparov, Sergey
    Diez-Freire, Carlos C.
    Raizada, Mohan K.
    Paton, Julian F. R.
    FASEB JOURNAL, 2008, 22
  • [22] Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate
    Evans, Catherine A.
    Liu, Tao
    Lescarbeau, Andre
    Nair, Somarajan J.
    Grenier, Louis
    Pradeilles, Johan A.
    Glenadel, Quentin
    Tibbitts, Thomas
    Rowley, Ann M.
    DiNitto, Jonathan P.
    Brophy, Erin E.
    O'Hearn, Erin L.
    Ali, Janid A.
    Winkler, David G.
    Goldstein, Stanley I.
    O'Heam, Patrick
    Martin, Christian M.
    Hoyt, Jennifer G.
    Soglia, John R.
    Cheung, Culver
    Pink, Melissa M.
    Proctor, Jennifer L.
    Palombella, Vito J.
    Tremblay, Martin R.
    Castro, Alfredo C.
    ACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (09): : 862 - 867
  • [23] Role of PI3K in the bone resorption of apical periodontitis
    Wang, LiNa
    Dong, Ming
    Shi, DongMei
    Yang, CaiHui
    Liu, Shuo
    Gao, Lu
    Niu, WeiDong
    BMC ORAL HEALTH, 2022, 22 (01)
  • [24] Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption
    Chang, Eun-Ju
    Ha, Jeongim
    Oerlemans, Frank
    Lee, You Jin
    Lee, Soo Woong
    Ryu, Jiyoon
    Kim, Hyung Joon
    Lee, Youngkyun
    Kim, Hyun-Man
    Choi, Je-Yong
    Kim, Jin Young
    Shin, Chan Soo
    Pak, Youngmi Kim
    Tanaka, Sakae
    Wieringa, Be
    Lee, Zang Hee
    Kim, Hong-Hee
    NATURE MEDICINE, 2008, 14 (09) : 966 - 972
  • [25] Role of PI3K in the bone resorption of apical periodontitis
    LiNa Wang
    Ming Dong
    DongMei Shi
    CaiHui Yang
    Shuo Liu
    Lu Gao
    WeiDong Niu
    BMC Oral Health, 22
  • [26] Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption
    Schmidt, Sarah
    Nakchbandi, Inaam
    Ruppert, Raphael
    Kawelke, Nina
    Hess, Michael W.
    Pfaller, Kristian
    Jurdic, Pierre
    Faessler, Reinhard
    Moser, Markus
    JOURNAL OF CELL BIOLOGY, 2011, 192 (05): : 883 - 897
  • [27] Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption
    Eun-Ju Chang
    Jeongim Ha
    Frank Oerlemans
    You Jin Lee
    Soo Woong Lee
    Jiyoon Ryu
    Hyung Joon Kim
    Youngkyun Lee
    Hyun-Man Kim
    Je-Yong Choi
    Jin Young Kim
    Chan Soo Shin
    Youngmi Kim Pak
    Sakae Tanaka
    Bé Wieringa
    Zang Hee Lee
    Hong-Hee Kim
    Nature Medicine, 2008, 14 : 966 - 972
  • [28] Rho/Rho kinase and Phosphoinositide-3-kinase (PI3K) are parallel pathways in development of spontaneous arterial tone in deoxycorticosterone acetate (DOCA)-salt hypertension
    Wehrwein, EA
    Northcott, CA
    Loberg, RD
    Watts, SW
    FASEB JOURNAL, 2004, 18 (04): : A307 - A307
  • [29] Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function
    Fung-Leung, Wai-Ping
    CELLULAR SIGNALLING, 2011, 23 (04) : 603 - 608
  • [30] Selective cathepsin K inhibitors prevent osteoclast-mediated bone resorption in vitro and in vivo.
    Drake, FH
    James, IE
    Bradbeer, J
    Tomaszek, T
    Bossard, M
    Levy, M
    Janson, C
    Smith, W
    Zhao, B
    McQueney, M
    Desjarlais, R
    LeeRykaczewski, E
    Zembryki, D
    Yamashita, D
    Marquis, R
    Halbert, S
    Thompson, S
    Veber, D
    Gowen, M
    JOURNAL OF BONE AND MINERAL RESEARCH, 1997, 12 : T369 - T369
12345