Celiac disease screening in Brazilian patients with osteoporosis

被引：4

作者：

Gusso, Luiza ^{[1
]}

Simoes, Mariana Cionek ^{[1
]}

Skare, Thelma L. ^{[1
]}

Nisihara, Renato ^{[2
]}

Burkiewicz, Claudine C. ^{[1
]}

Utiyama, Shirley ^{[3
]}

机构：

[1] Hosp Univ Evangel Curitiba, Rheumatol Unit, BR-80240000 Curitiba, PR, Brazil

[2] Univ Posit, BR-80240000 Curitiba, PR, Brazil

[3] Univ Fed Parana UFPR, Clin Hosp, Immunopathol Lab, Curitiba, PR, Brazil

来源：

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2014年 / 58卷 / 03期

关键词：

Osteoporosis; celiac disease; auto-antibodies; gluten; PREVALENCE; BONE; FRACTURES;

D O I：

10.1590/0004-2730000002919

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: To analyze if it is worthwhile to screen Brazilian osteoporotic patients for celiac disease (CD). Subjects and methods: One hundred patients with osteoporosis and 97 controls were evaluated for IgA-EmA (IgA anti-endomysial antibodies) by indirect immunofluorescence method and IgG-anti-tTG (tissue transglutaminase) by ELISA assay. Positive patients were invited to have gastrointestinal endoscopy with jejunal biopsy. Results: Two patients had positive IgG-anti-tTG test and one of them also showed positive IgA-EmA. Only the latter had a positive duodenal biopsy for CD. None of the controls were positive for either auto-antibodies. Conclusion: We observed low prevalence of CD in osteoporotic Brazilian patients. This finding does not support routine screening for CD in patients with osteoporosis in our geographic region.

引用

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页码：270 / 273

页数：4

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