Celiac disease screening in Brazilian patients with osteoporosis

被引：4
|
作者：
Gusso, Luiza [1 ]
Simoes, Mariana Cionek [1 ]
Skare, Thelma L. [1 ]
Nisihara, Renato [2 ]
Burkiewicz, Claudine C. [1 ]
Utiyama, Shirley [3 ]
机构：
[1] Hosp Univ Evangel Curitiba, Rheumatol Unit, BR-80240000 Curitiba, PR, Brazil
[2] Univ Posit, BR-80240000 Curitiba, PR, Brazil
[3] Univ Fed Parana UFPR, Clin Hosp, Immunopathol Lab, Curitiba, PR, Brazil
来源：
ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2014年 / 58卷 / 03期
关键词：
Osteoporosis; celiac disease; auto-antibodies; gluten; PREVALENCE; BONE; FRACTURES;
D O I：
10.1590/0004-2730000002919
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To analyze if it is worthwhile to screen Brazilian osteoporotic patients for celiac disease (CD). Subjects and methods: One hundred patients with osteoporosis and 97 controls were evaluated for IgA-EmA (IgA anti-endomysial antibodies) by indirect immunofluorescence method and IgG-anti-tTG (tissue transglutaminase) by ELISA assay. Positive patients were invited to have gastrointestinal endoscopy with jejunal biopsy. Results: Two patients had positive IgG-anti-tTG test and one of them also showed positive IgA-EmA. Only the latter had a positive duodenal biopsy for CD. None of the controls were positive for either auto-antibodies. Conclusion: We observed low prevalence of CD in osteoporotic Brazilian patients. This finding does not support routine screening for CD in patients with osteoporosis in our geographic region.
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页码：270 / 273
页数：4
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