4-Alkylated 2-(2,3,5-Tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)-1,2,4-triazine-3,5-diones

被引：2

作者：

Harutyunyan, A. A. ^{[1
,2
]}

Panosyan, H. A. ^{[1
]}

Tamazyan, R. A. ^{[1
]}

Aivazyan, A. G. ^{[1
]}

Danagulyan, G. G. ^{[1
,2
]}

机构：

[1] Natl Acad Sci Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Mndzhoyan Inst Fine Organ Chem, Pr Azatutyan 26, Yerevan 0014, Armenia

[2] Russian Armenian Slav Univ, Ul Ovsela Emina 123, Yerevan 0051, Armenia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 53卷 / 04期

关键词：

6-AZAURACIL;

D O I：

10.1134/S1070428017040121

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The alkylation of 2-(2,3,5-tri-O-acyl-beta-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)- 1,2,4-triazine-3,5-diones with benzyl halides afforded the corresponding 4-benzyl derivatives whose structure was determined by spectral methods, including X-ray analysis. Some of the synthesized compounds were tested for antibacterial and antitumor activity.

引用

页码：573 / 576

页数：4

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