4-Alkylated 2-(2,3,5-Tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)-1,2,4-triazine-3,5-diones

被引：2
|
作者：
Harutyunyan, A. A. [1 ,2 ]
Panosyan, H. A. [1 ]
Tamazyan, R. A. [1 ]
Aivazyan, A. G. [1 ]
Danagulyan, G. G. [1 ,2 ]
机构：
[1] Natl Acad Sci Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Mndzhoyan Inst Fine Organ Chem, Pr Azatutyan 26, Yerevan 0014, Armenia
[2] Russian Armenian Slav Univ, Ul Ovsela Emina 123, Yerevan 0051, Armenia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 53卷 / 04期
关键词：
6-AZAURACIL;
D O I：
10.1134/S1070428017040121
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The alkylation of 2-(2,3,5-tri-O-acyl-beta-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)- 1,2,4-triazine-3,5-diones with benzyl halides afforded the corresponding 4-benzyl derivatives whose structure was determined by spectral methods, including X-ray analysis. Some of the synthesized compounds were tested for antibacterial and antitumor activity.
引用
收藏
页码：573 / 576
页数：4
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