Pharmacodynamics and the relationship between in vitro and in vivo activity of antimicrobial agents

被引：0
|
作者：
Gould, IM
机构：
来源：
JOURNAL OF CHEMOTHERAPY | 1997年 / 9卷
关键词：
post-antibiotic effect; beta-lactam dosing; pharmacodynamics;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This article discusses the various in vitro and in vivo models used to investigate the pharmacodynamics of antibiotic action and relates this to clinical use of antibiotics. The dosing of beta-lactams is discussed in detail, particularly in relation to the method dependence of the various models of post antibiotic effect (PAE) and the different morphological farms that are produced by different beta-lactams.
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页码：74 / 83
页数：10
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