Using Human iPSCs for Psychiatric Disorder Disease Modeling and Mechanism-Based Drug Discovery

被引：1

作者：

Wen, Zhexing ^{[1
,2
]}

Guo, Ziyuan ^{[1
]}

Wang, Xinyuan ^{[1
]}

Kim, Namshik ^{[1
]}

Ross, Christopher ^{[1
]}

Margolis, Russell ^{[1
]}

Christian, Kimberly ^{[1
]}

Chen, Gong ^{[3
]}

Zheng, Wei ^{[4
]}

Xia, Menghang ^{[4
]}

Song, Hongjun ^{[1
]}

Ming, Guo-li ^{[1
]}

机构：

[1] Johns Hopkins Univ, Baltimore, MD 21218 USA

[2] Emory Univ, Atlanta, GA 30322 USA

[3] Penn State Univ, University Pk, PA 16802 USA

[4] Natl Ctr Advancing Translat Sci, Bethesda, MD USA

来源：

BIOLOGICAL PSYCHIATRY | 2017年 / 81卷 / 10期

关键词：

Schizophrenia; hIPSC; synapses; disease modeling;

D O I：

10.1016/j.biopsych.2017.02.784

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

717

引用

页码：S290 / S291

页数：2

共 50 条

[21] Impact of mechanism-based enzyme inactivation on inhibitor potency: Implications for rational drug discovery
Maurer, TS
Tabrizi-Fard, MA
Fung, HL
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 2000, 89 (11) : 1404 - 1414
[22] Prediction of drug-drug interaction caused by a mechanism-based CYP inhibitor in human
Kato, M
Higashida, A
Mitsui, T
Sakai, S
Aso, Y
[J]. DRUG METABOLISM REVIEWS, 2004, 36 : 285 - 285
[23] Mechanism-based modeling of friction and wear
Ludema, KC
[J]. WEAR, 1996, 200 (1-2) : 1 - 7
[24] Disease modelling using human iPSCs
Chamberlain, Stormy J.
[J]. HUMAN MOLECULAR GENETICS, 2016, 25 (R2) : R173 - R181
[25] Human pluripotent stem cell-based cardiovascular disease modeling and drug discovery
Liu, Ge
Liu, Zhun
Cao, Nan
[J]. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2021, 473 (07): : 1087 - 1097
[26] Human iPSC-based retinal cell library for disease modeling and drug discovery
Reichman, Sacha
Nanteau, Celine
Clemencon, Marilou
Lechuga, Marc
Guillonneau, Xavier
Sahel, Jose-Alain
Goureau, Olivier
Gozlan, Sandy
[J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2022, 63 (07)
[27] Mechanism-based Drug Therapy of Inflammatory Bowel Disease With Special Reference to Rheumatic Disease
Park, Jae Jun
[J]. JOURNAL OF RHEUMATIC DISEASES, 2020, 27 (03): : 128 - 135
[28] Mechanism-Based Discovery of Novel Substrates of Haloalkane Dehalogenases Using in Silico Screening
Daniel, Lukas
Buryska, Tomas
Prokop, Zbynek
Damborsky, Jiri
Brezovsky, Jan
[J]. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2015, 55 (01) : 54 - 62
[29] Human Stem Cells for Modeling Heart Disease and for Drug Discovery
Matsa, Elena
Burridge, Paul W.
Wu, Joseph C.
[J]. SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (239)
[30] Disease Modeling of Fanconi Anemia in Human iPSCs.
Ruiz-Torres, S.
Brusadelli, M. G.
Sauter, S.
Zhao, X.
Zhang, W.
Davies, S. M.
Mehta, P.
Myers, K.
Nelson, A.
Chlon, T. M.
Witte, D. P.
Wikenheiser-Brokamp, K. A.
Setchell, K. D.
Butsch-Kovacic, M.
Wells, S., I
[J]. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2016, 57 : S41 - S41

← 1 2 3 4 5 →