Synthesis of 3,4-dihydro-2H-pyrido[1,2-b]isoindol-1-one and 3,4-dihydro-2H-pyrido[1,2-b]pyrrolidin-1-one functionalized at the C-6 position by an intramolecular Horner-Wadsworth-Emmons reaction

被引:0
|
作者
Gourves, JP [1 ]
Couthon, H [1 ]
Sturtz, G [1 ]
机构
[1] UFR Sci & Tech, Lab Chim Heteroorgan, F-29285 Brest, France
关键词
methylene-1,1-bisphosphonate; 3-bromoalkylimide; Horner-Wadsworth-Emmons reaction phosphonate complexes; heterocyclic compounds; cyclizations;
D O I
10.1002/(SICI)1099-0690(199912)1999:12<3489::AID-EJOC3489>3.0.CO;2-F
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel polyheterocycles were prepared from a new annellation reaction which proceeds by nucleophilic substitution followed by an intramolecular Horner-Wads-worth-Emmons reaction between imides and beta-functionalized phosphonates.
引用
收藏
页码:3489 / 3493
页数:5
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