SnCl2-catalyzed three-component one-pot Mannich-type reaction: efficient synthesis of β-aminocarbonyl compounds

被引：19
|
作者：
Wang, Min [1 ]
Song, Zhi-Guo [2 ]
Wan, Xin [1 ]
Zhao, Suang [1 ]
机构：
[1] Bohai Univ, Coll Chem & Chem Engn, Jinzhou, Peoples R China
[2] Bohai Univ, Ctr Sci & Technol Expt, Jinzhou, Peoples R China
来源：
MONATSHEFTE FUR CHEMIE | 2009年 / 140卷 / 10期
关键词：
Mannich reaction; beta-Aminocarbonyl compound; One-pot synthesis; SnCl2; ASYMMETRIC MANNICH; AROMATIC-ALDEHYDES; KETONES; CATALYSTS;
D O I：
10.1007/s00706-009-0163-1
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
SnCl2-catalyzed three-component one-pot Mannich reaction of acetophenone or p-chloroacetophenone with different aromatic aldehydes and aromatic amines in ethanol at ambient temperature gave the corresponding beta-aminocarbonyl compounds in good to excellent yields. Four new compounds are reported for the first time.
引用
收藏
页码：1205 / 1208
页数：4
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