The facile and efficient three-component one-pot Mannich-type reaction of indoles catalyzed by In(OTf)3 under microwave irradiations

被引：6

作者：

Prajapati, Dipak ^{[1
]}

Gadhwal, Sunil ^{[1
]}

Sarma, Rupam ^{[1
]}

机构：

[1] NE Inst Sci & Technol, Dept Med Chem, Jorhat 785006, Assam, India

来源：

LETTERS IN ORGANIC CHEMISTRY | 2008年 / 5卷 / 05期

关键词：

indoles; indium triflate; microwave irradiations; multicomponent reactions; Mannich-type reactions; bisindolyl methane;

D O I：

10.2174/157017808784872133

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indium triflate catalysed the three-component one-pot reaction of indole 1 with a heteroimine generated in situ under microwave irradiations and afforded predominately secondary indolyl amines 4 in excellent yields as well as bisindolyl methane 5 in poor yields. The catalyst indium triflate can be recovered after the reaction and reused in the subsequent experiments.

引用

页码：365 / 369

页数：5

共 50 条

[1] One-pot, three-component Mannich-type reaction catalyzed by functionalized ionic liquid
Dong Fang
Kai Gong
Dai-zhen Zhang
Zu-liang Liu
[J]. Monatshefte für Chemie - Chemical Monthly, 2009, 140 : 1325 - 1329
[2] One-pot three-component Mannich-type reaction catalyzed by trifluoromethanesulfonic acid in water
Gang Li
Hankui Wu
Zhiyong Wang
Xianli Wang
[J]. Kinetics and Catalysis, 2011, 52 : 89 - 93
[3] One-Pot Three-Component Mannich-Type Reaction Catalyzed by Trifluoromethanesulfonic Acid in Water
Li Gang
Wu Hankui
Wang Zhiyong
Wang Xianli
[J]. KINETICS AND CATALYSIS, 2011, 52 (01) : 89 - 93
[4] One-pot, three-component Mannich-type reaction catalyzed by functionalized ionic liquid
Fang, Dong
Gong, Kai
Zhang, Dai-zhen
Liu, Zu-liang
[J]. MONATSHEFTE FUR CHEMIE, 2009, 140 (11): : 1325 - 1329
[5] SnCl2-catalyzed three-component one-pot Mannich-type reaction: efficient synthesis of β-aminocarbonyl compounds
Min Wang
Zhi-Guo Song
Xin Wan
Suang Zhao
[J]. Monatshefte für Chemie - Chemical Monthly, 2009, 140 : 1205 - 1208
[6] SnCl2-catalyzed three-component one-pot Mannich-type reaction: efficient synthesis of β-aminocarbonyl compounds
Wang, Min
Song, Zhi-Guo
Wan, Xin
Zhao, Suang
[J]. MONATSHEFTE FUR CHEMIE, 2009, 140 (10): : 1205 - 1208
[7] Three-component Mannich-type reaction catalyzed by iodine
Kataki, Dolly
Phukan, Prodeep
[J]. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2006, 45 (07): : 1759 - 1761
[8] EFFICIENT SYNTHESIS OF PURINE DERIVATIVES BY ONE-POT THREE-COMPONENT MANNICH TYPE REACTION
Zhang, Qian
Ma, Bai-Wei
Huang, Yong-Zhen
Wang, Qian-Qian
Wang, Xing-Xing
Qu, Gui-Rong
Guo, Hai-Ming
[J]. HETEROCYCLES, 2013, 87 (10) : 2081 - 2091
[9] Highly efficient one-pot three-component Mannich reaction in water catalyzed by heteropoly acids
Azizi, N
Torkiyan, L
Saidi, MR
[J]. ORGANIC LETTERS, 2006, 8 (10) : 2079 - 2082
[10] Squaric Acid Catalyzed Highly Efficient Three-Component Mannich-Type Reaction
Azizi, Najmadin
Davoudpour, Anahita
[J]. CATALYSIS LETTERS, 2011, 141 (10) : 1506 - 1510

← 1 2 3 4 5 →