Crosstalk Between Mucosal Inflammation and Bone Metabolism in Chronic Rhinosinusitis

被引：17

作者：

Khalmuratova, Roza ^{[1
]}

Shin, Hyun-Woo ^{[1
,2
,3
,4
,5
]}

机构：

[1] Seoul Natl Univ, Coll Med, Dept Pharmacol, Obstruct Upper Airway Res OUaR Lab, Seoul, South Korea

[2] Seoul Natl Univ, Coll Med, Dept Biomed Sci, Seoul, South Korea

[3] Seoul Natl Univ, Coll Med, Ischem Hypox Dis Inst, Seoul, South Korea

[4] Seoul Natl Univ, Coll Med, Canc Res Inst, Seoul, South Korea

[5] Seoul Natl Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, 103 Daehak Ro, Seoul 03080, South Korea

来源：

CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY | 2021年 / 14卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

Osteitis; Chronic Rhinosinusitis; Inflammation; Osteoblasts; Osteoclasts; Cytokine; EOSINOPHILIC CHRONIC RHINOSINUSITIS; P-GLYCOPROTEIN; NASAL POLYPS; GENE-EXPRESSION; COMPUTED-TOMOGRAPHY; TISSUE EOSINOPHILIA; CHRONIC SINUSITIS; ENTEROTOXIN-B; CT ANALYSIS; OSTEITIS;

D O I：

10.21053/ceo.2020.00416

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Chronic rhinosinusitis (CRS) is a multifactorial and highly heterogeneous upper airway disease that affects approximately 12% of the general population. There is increasing evidence supporting the impact of osteitis on the pathophysiology of CRS. Osteitis is frequently observed in patients with CRS, and is associated with severe sinonasal inflammation and recalcitrant cases. The overlying inflammatory sinonasal mucosa plays a critical role in the initiation of osteitis; however, the underlying molecular mechanisms and functional significance remain unclear. Increasingly many studies have suggested that immune cells play a crucial role in the bone remodeling process in CRS. The purpose of this review is to summarize the current state of knowledge regarding the specific role of sinonasal inflammation in bone remodeling in CRS patients.

引用

页码：43 / 49

页数：7

共 50 条

[1] Association of Mucosal Organisms with Patterns of Inflammation in Chronic Rhinosinusitis
Chalermwatanachai, Thanit
Zhang, Nan
Holtappels, Gabriele
Bachert, Claus
[J]. PLOS ONE, 2015, 10 (08):
[2] Relationship between mucosal inflammation, computed tomography, and symptomatology in chronic rhinosinusitis without polyposis
Bhattacharyya, Neil
[J]. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2008, 117 (07): : 517 - 522
[3] Crosstalk between cholesterol metabolism and psoriatic inflammation
Luo, Lingling
Guo, Youming
Chen, Lihao
Zhu, Jing
Li, Chengrang
[J]. FRONTIERS IN IMMUNOLOGY, 2023, 14
[4] Fractional Exhaled Nitric Oxide as a Marker of Mucosal Inflammation in Chronic Rhinosinusitis
Olonisakin, Tolani F.
Moore, John A.
Barel, Stephanie
Uribe, Bliss
Parker, Dana
Bowers, Eve M. R.
Nouraie, Seyed M.
Wenzel, Sally E.
Lee, Stella E.
[J]. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2022, 36 (04) : 465 - 472
[5] Mucosal remodeling in chronic rhinosinusitis
Rehl, Ryan M.
Balla, Andre A.
Cabay, Robert J.
Hearp, Matthew L.
Pytynia, Kristin B.
Joe, Stephanie A.
[J]. AMERICAN JOURNAL OF RHINOLOGY, 2007, 21 (06): : 651 - 657
[6] Chloroquine Treatment Suppresses Mucosal Inflammation in a Mouse Model of Eosinophilic Chronic Rhinosinusitis
Choi, Mi-Ra
Xu, Jun
Lee, Seulgi
Yeon, Sun-Hee
Park, Soo-Kyoung
Rha, Ki-Sang
Kim, Yong Min
[J]. ALLERGY ASTHMA & IMMUNOLOGY RESEARCH, 2020, 12 (06) : 994 - 1011
[7] Crosstalk Between Autophagy and Inflammation in Chronic Cerebral Ischaemia
Hai-qian Zhou
Li-mei Zhang
Xiao Li
Zhi-hua Huang
[J]. Cellular and Molecular Neurobiology, 2023, 43 : 2557 - 2566
[8] Crosstalk Between Autophagy and Inflammation in Chronic Cerebral Ischaemia
Zhou, Hai-qian
Zhang, Li-mei
Li, Xiao
Huang, Zhi-hua
[J]. CELLULAR AND MOLECULAR NEUROBIOLOGY, 2023, 43 (06) : 2557 - 2566
[9] Impact of Chronic Inflammation in Psoriasis on Bone Metabolism
Saalbach, Anja
Kunz, Manfred
[J]. FRONTIERS IN IMMUNOLOGY, 2022, 13
[10] Mucosal remodeling and reversibility in chronic rhinosinusitis
Bassiouni, Ahmed
Chen, Philip G.
Wormald, Peter-John
[J]. CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 13 (01) : 4 - 12

← 1 2 3 4 5 →