A synthesis and transformations of alkyl 2-[2-cyano-2-(2-pyridinyl)ethenyl]amino-3-dimethylaminopropenoates.: A one-pot synthesis of pyrrolo[3,2-d]pyrimidin-4-ones

被引:0
|
作者
Jukic, L [1 ]
Svete, J [1 ]
Golobic, A [1 ]
Golic, L [1 ]
Stanovnik, B [1 ]
机构
[1] Univ Ljubljana, Fac Chem & Chem Technol, Ljubljana 1000, Slovenia
关键词
2-[2-cyano-2-(2-pyridinyl)ethenyl]amino-3-aminopropenoate; 4-pyridinyl-3-(2-aminovinyl)aminopyrrole;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Alkyl 2-[2-cyano-2-(2-pyridinyl)ethenyl]amino-3-dimethylaminopropenoates (8) and (9) were transformed by heating into alkyl 2-[2-cyano-2-(2-pyridinyl)ethenyl]amino-3-[2-methoxycabonyl-4-(2-pyridinyl)-1H-pyrrol-3-yl]aminopropenoates (12) and (13). Compounds (8) and (9) can be transformed in the presence of primary aliphatic amines into substituted pyrrolo[3,2-d]pyrimidines (17-19).
引用
收藏
页码:805 / 820
页数:16
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