The azaallylic anion as a synthon for Pd-catalyzed synthesis of heterocycles:: Domino two- and three-component synthesis of indoles

被引：116
|
作者：
Barluenga, Jose [1 ]
Jimenez-Aquino, Agustin [1 ]
Valdes, Carlos [1 ]
Aznar, Fernando [1 ]
机构：
[1] Univ Oviedo, Inst Quim Organomet Enrique Moles, Unidad Asociada, E-33071 Oviedo, Spain
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 09期
关键词：
arylation; indoles; multicomponent reactions; palladium; synthetic methods;
D O I：
10.1002/anie.200604407
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Piecing it all together with palladium: Two- and three-component cascade processes that are promoted by a multifunctional Pd catalyst lead to indoles in a highly efficient manner (see scheme). The key step is the Pd-catalyzed α-arylation of imines with o-dihalobenzene derivatives. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：1529 / 1532
页数：4
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