"On Water" promoted N-arylation reactions using Cu (0)/myo-inositol catalytic system

被引：7
|
作者：
Zhou, Qifan [1 ]
Du, Fangyu [1 ]
Chen, Yuanguang [1 ]
Fu, Yang [1 ]
Chen, Guoliang [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China
来源：
TETRAHEDRON LETTERS | 2019年 / 60卷 / 29期
关键词：
Myo-inositol; N-Arylation; Copper; Water; ARYL HALIDES; COUPLING REACTIONS; AMINO-ACIDS; COPPER; INHIBITION; AMINATION; EFFICIENT; ANALOGS; KINASE; MYOINOSITOL;
D O I：
10.1016/j.tetlet.2019.06.033
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Myo-inositol is originally applied as a cardiovascular medicine in clinic, which can be multi-ton manufactured via extraction from the byproducts in agricultural product processing such as defatted rice bran and corn-soaking water. Herein, the application of myo-inositol (MI) as a novel versatile tridentate O-donor ligand has been first described for promoting Cu-catalyzed amination reaction in aqueous medium. (C) 2019 Published by Elsevier Ltd.
引用
收藏
页码：1938 / 1941
页数：4
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