Getting hotter with RNA

被引:6
|
作者
Sosnick, TR
Pan, T
机构
[1] Univ Chicago, Dept Biochem & Mol Biol, Chicago, IL 60637 USA
[2] Univ Chicago, Inst Biophys Dynam, Chicago, IL 60637 USA
关键词
D O I
10.1038/nsb1102-795
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Results from in vitro selection studies reveal that enhanced ribozyme stability can be achieved through a small number of substitutions, which primarily improve the packing interactions in the molecular interior.
引用
收藏
页码:795 / 796
页数:2
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