A CMOS-based Neural Implantable Optrode for Optogenetic Stimulation and Electrical Recording

被引：0

作者：

Zhao, Hubin ^{[1
]}

Dehkhoda, Fahimeh ^{[1
]}

Ramezani, Reza ^{[1
]}

Sokolov, Danil ^{[1
]}

Degenaar, Patrick ^{[1
]}

Liu, Yan ^{[2
]}

Constandinou, Timothy ^{[2
]}

机构：

[1] Newcastle Univ, Sch Elect & Elect Engn, Newcastle Upon Tyne, Tyne & Wear, England

[2] Imperial Coll London, Dept Elect & Elect Engn, London, England

来源：

2015 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS) | 2015年

基金：

英国惠康基金;

关键词：

CIRCUIT;

D O I：

暂无

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

This paper presents a novel integrated optrode for simultaneous optical stimulation and electrical recording for closed-loop optogenetic neuro-prosthetic applications. The design has been implemented in a commercially available 0.35 mu m CMOS process. The system includes circuits for controlling the optical stimulations; recording local field potentials (LFPs); and onboard diagnostics. The neural interface has two clusters of stimulation and recording sites. Each stimulation site has a bonding point for connecting a micro light emitting diode (mu LED) to deliver light to the targeted area of brain tissue. Each recording site is designed to be post-processed with electrode materials to provide monitoring of neural activity. On-chip diagnostic sensing has been included to provide real-time diagnostics for post-implantation and during normal operation.

引用

页码：286 / 289

页数：4

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